ArticleScience immunology2021
A reservoir of stem-like CD8
Abstract read
In one paragraph
Article in Science immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 295 papers, 2 of them syntheses that pooled it.
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0cells of the map it votes in
295citing papers in PubMed, 2 pooled it
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
295 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pooled it
- The Optimal First-Line Therapy for Extensive-Stage Small-Cell Lung Cancer Based on Liver Metastasis Status: A Network Meta-Analysis and Systematic Review.Cancer medicine · 2024Pooled it
- Tumor-Regional Immune Microenvironment: A Critical Factor in the Design of Radiotherapy-Immunotherapy Combination Trials.International journal of cancer · 2026Review
- Article
- T cell immunomonitoring: a comparative analysis of traditional and novel methods to quantify and characterize human antigen-specific T cells.Nature protocols · 2026Review
- Spatial and Single-Cell Multi-Omics Analyses of T-Cell Subsets and Interactions in Melanoma Lymph Node Metastasis.Experimental dermatology · 2026Review
- Mechanisms of systemic immune modulation in tumor development: Interactions across lymph nodes, bone marrow, and blood.Cancer metastasis reviews · 2026Review
- Review
- The next 25 years of cancer research: emerging perspectives and priorities.Nature reviews. Cancer · 2026Article
- Article
- Immune-pressure redistribution in resistance to PD-1/PD-L1 blockade: mechanisms, biomarkers, and therapeutic design.Molecular cancer · 2026Review
- Dendritic cell PD-L2 restrains intratumoral CD8bioRxiv : the preprint server for biology · 2026Article
- Epigenetic plus cytokine therapy induces stem-like CD8Journal for immunotherapy of cancer · 2026Article
- Phenotypic and functional characterization of tumor-reactive T cells in malignant pleural effusions.Cancer immunology research · 2026Article
- Photothermal-driven sequential immunotherapy overcomes resistance to PARP inhibition inActa pharmaceutica Sinica. B · 2026Article
- Exploiting the CXCR3/CXCL10 axis overrides tumor immune suppression by enhancing immune trafficking and effector cell priming in HNSCC.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Clonal sharing and plasticity of follicular CD4 + T cells across lymph nodes and tumors in non-small cell lung cancer.Nature communications · 2026Article
- Tumor-distal mediastinal lymph nodes harbor tumor-related progenitor exhausted T cells in lung cancer after neoadjuvant chemoimmunotherapy.Cell reports. Medicine · 2026Article
- Radiotherapy and immunotherapy in cancer treatment: mechanisms of clinical synergy.The Journal of clinical investigation · 2026Review
- Spatial Immune Coding in Tumor-Draining Lymph Nodes: Functional Compartmentalization of Immune Activation and Immunosuppression.International journal of molecular sciences · 2026Review
235 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors.
Kelli A ConnollyDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA.ORCID 0000-0002-3403-1150
Manik KuchrooDepartment of Neuroscience, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0001-7512-9739
Aarthi VenkatComputational Biology and Bioinformatics Program, Yale University, New Haven, CT, USA.ORCID 0000-0003-0298-0172
Achia KhatunDepartment of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, WI, USA.
Jiawei WangComputational Biology and Bioinformatics Program, Yale University, New Haven, CT, USA.ORCID 0000-0003-2627-4897
Ivana WilliamDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA.
Noah I HornickDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA.ORCID 0000-0002-3503-7693
Brittany L FitzgeraldDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA.
Martina DamoDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA.ORCID 0000-0002-7217-3221
Moujtaba Y KasmaniDepartment of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, WI, USA.ORCID 0000-0002-5753-5335
Can CuiDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA.ORCID 0000-0003-4736-4330
Eric FagerbergDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA.ORCID 0000-0003-0313-3717
Isabel MonroyDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA.ORCID 0000-0003-3959-9324
Amanda HutchinsDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA.
Julie F CheungDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA.ORCID 0000-0003-1346-0930
Gena G FosterDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA.
Dylan L MariuzzaDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA.ORCID 0000-0002-9369-2514
Mursal NaderDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA.
Hongyu ZhaoDepartment of Biostatistics, Yale School of Public Health, New Haven, CT 06510, USA.ORCID 0000-0003-1195-9607
Weiguo CuiDepartment of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, WI, USA.
Smita KrishnaswamyDepartment of Genetics and Computer Science, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0001-5823-1985
Nikhil S JoshiDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA.ORCID 0000-0002-7045-7837
Funding
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9MYale Pathology Tissue Services Shared ResourceP30CA016359 · NCI · YALE UNIVERSITY · PI DAVID L RIMM · 1985 to 2026
$85.0MSystems investigation of vaccine responses in B cell depleted autoimmune patientsU19AI089992 · NIAID · YALE UNIVERSITY · PI David A. Hafler, RUTH R MONTGOMERY · 2010 to 2026
$50.4MYale SPORE in Lung Cancer (YSILC): The Biology and Personalized Treatment of Lung CancerP50CA196530 · NCI · YALE UNIVERSITY · PI Shuangge Ma · 2015 to 2026
$31.1MINTERDISCIPLINARY IMMUNOLOGY TRAINING PROGRAMT32AI007019 · NIAID · YALE UNIVERSITY · PI Carrie L. Lucas, David G. Schatz · 1985 to 2026
$14.4MIMMUNOHEMATOLOGY/TRANSFUSION MEDICINE RESEARCH TRAININGT32HL007974 · NHLBI · YALE UNIVERSITY · PI JEANNE E HENDRICKSON, Diane S Krause · 2001 to 2026
$8.1MTraining in Investigative DermatologyT32AR007016 · NIAMS · YALE UNIVERSITY · PI KEITH A CHOATE, MICHAEL GIRARDI · 1986 to 2026
$7.8MMedical Scientist Training ProgramT32GM080202 · NIGMS · MEDICAL COLLEGE OF WISCONSIN · PI BARBIERI, JOSEPH T, SALZMAN, NITA H · 2010 to 2024
$5.7MYale Cancer Center Advanced Training Program for Physician-Scientists (YCC-ATPP)T32CA233414 · NCI · YALE UNIVERSITY · PI Eric P. Winer · 2019 to 2026
$3.2MPhenotypic, Functional and Transcriptional Heterogeneity in T Cell ExhaustionR01AI148403 · NIAID · VERSITI WISCONSIN, INC. · PI WEIGUO CUI · 2020 to 2026
$3.1MDeveloping translationally-relevant genetically engineered mouse models of lung adenocarcinoma for investigations in cancer immunologyR01CA237037 · NCI · YALE UNIVERSITY · PI JOSHI, NIKHIL · 2020 to 2024
$2.7MHuman and Translational Immunology Training ProgramT32AI155387 · NIAID · YALE UNIVERSITY · PI Joseph Edgar Craft, Kevan C Herold · 2021 to 2026
$2.6MNCATS NIH HHS UL1 TR001863NCI NIH HHS K22 CA200912NCI NIH HHS P30 CA016359NCI NIH HHS P50 CA196530NCI NIH HHS R01 CA237037NCI NIH HHS T32 CA233414NHLBI NIH HHS T32 HL007974NIAID NIH HHS R01 AI125741NIAID NIH HHS R01 AI148403NIAID NIH HHS T32 AI007019NIAID NIH HHS T32 AI155387NIAID NIH HHS U19 AI089992NIAMS NIH HHS T32 AR007016NIDDK NIH HHS F30 DK127526NIGMS NIH HHS T32 GM080202
Abstract
“Stem-like” TCF1
Indexed as
AnimalsCD8-Positive T-LymphocytesFemaleImmunotherapyLung NeoplasmsLymph NodesLymphocyte ActivationMaleMiceMice, Inbred C57BLTumor Microenvironment
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.