Evidence map›Paper›PMID 34596752›Full record

ArticlePflugers Archiv : European journal of physiology2021

Mechanisms underlying spontaneous phasic contractions and sympathetic control of smooth muscle in the rat caudal epididymis.

Retsu Mitsui, Hikaru Hashitani, Richard J Lang, Dirk F van Helden

Abstract read
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In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Identification of Catecholamine and Drug Target αJournal of clinical medicine · 2024
    Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Retsu MitsuiDepartment of Cell Physiology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Hikaru HashitaniDepartment of Cell Physiology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Richard J LangDepartment of Physiology, Faculty of Medicine, Nursing and Health Sciences, School of Biomedical Sciences, Monash University, Clayton, Australia.
Dirk F van HeldenSchool of Biomedical Sciences and Pharmacy and Hunter Medical Research Institute, Faculty of Health and Medicine, The University of Newcastle, Callaghan, NSW, 2308, Australia. dirk.vanhelden@newcastle.edu.au.ORCID http://orcid.org/0000-0002-5631-6579
Nagoya City University · JPHunter Medical Research Institute · AUMonash University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here we investigate mechanisms underlying spontaneous phasic contractions (SPCs) and sympathetic control of contractility in the rat epididymis, a long tubular duct involved in transportation and maturation of sperm. Longitudinal contractions of short segments (~ 1.5 mm) of rat proximal and distal caudal epididymal duct were measured + / - nerve stimulation. The extent of sympathetic innervation of these duct regions was determined by immunohistochemistry. Proximal caudal duct segments (150-300 μm dia.) exhibited SPCs, while distal segments (350-500 μm) were quiescent in ~ 80% of preparations. SPC amplitude and frequency were reduced by the L-type voltage-dependent Ca

Indexed as

AnimalsCalcium Channel BlockersCalcium Channels, L-TypeEpididymisMaleMuscle ContractionMuscle, SmoothNifedipineNorepinephrinePhenylephrineRatsRats, WistarRyanodineSympathetic Nervous SystemCalcium Channel BlockersCalcium Channels, L-TypeNifedipineNorepinephrinePhenylephrineRyanodineAlpha-adrenergic receptorsCaudal epididymisMale reproductive systemSmooth muscleSpontaneous phasic contractionsSympathetic nerves

Identifiers

PMID34596752
OpenAlexW3204193534

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.