ArticleJournal of neurology2022
Self-injurious behavior in Tourette syndrome.
Article in Journal of neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 25 citations in OpenAlex.
- Tourette syndrome.Nature reviews. Disease primers · 2026Review
- Pharmacological and Non-Pharmacological Interventions for Non-Suicidal Self-Injury: A Narrative Review.Alpha psychiatry · 2026Review
- Botulinum Toxin for the Treatment of Motor Tics in Children: A Case Series.Journal of child neurology · 2026Article
- Stigma and risk of self-injury and suicidality in adults with Tourette syndrome: findings from a cross-sectional impact survey.BMJ open · 2026Article
- Epidemiology of Tourette Syndrome.Brain sciences · 2025Review
- Pain in Tourette Syndrome: A Comprehensive Review.Journal of child and adolescent psychopharmacology · 2025Review
- Traditional Chinese Medicine in the Comprehensive Management of Tourette Syndrome: Insights from Genetics and Pathophysiology: A Review.Drug design, development and therapy · 2025Review
- A Critical Examination of the Clinical Diagnosis of Functional Tic-like Behaviors.Movement disorders clinical practice · 2024Review
- Deep brain stimulation for Tourette's syndrome.The Cochrane database of systematic reviews · 2024Article
- Validation and assessment of the self-injurious behavior scale for tic disorders (SIBS-T).Scientific reports · 2024Article
- Article
- Tourette syndrome: clinical features, pathophysiology, and treatment.The Lancet. Neurology · 2023Review
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionTourette syndrome (TS) is characterized by the presence of motor and phonic tics, as well as a variety of behavioral co-morbidities. Self-injurious behavior (SIB) is one of the most serious manifestations of TS, but its pathophysiology is poorly understood.
methodsConsecutive patients with TS studied in a tertiary care center.
resultsWe identified a total of 34 patients (16.9%) with SIB from a cohort of 201 patients with TS. Most of these patients (n = 23, 11.4%) experienced self-directed damage; while others had outward-directed (n = 7, 3.5%) or tic-related SIB (n = 4, 2%). Compared to other patients with TS, those who manifested SIB (self- and outward-directed damage) were more likely to have tics involving shoulder (P = 0.046), trunk (P = 0.006), and arm (P = 0.017); as well as dystonic tics (P = 0.016); complex motor tics (P < 0.001), copropraxia (P = 0.045), complex phonic tics (P = 0.003), higher number of phonic tics (P = 0.001), verbalizations (P = 0.001), coprolalia (P = 0.006) and obsessive compulsive disorder (OCD) (P < 0.001) as determined by bivariate analysis. In the multivariate analysis only complex motor tics (P = 0.006), obsessive-compulsive behavior (P = 0.025) and greater severity of tics (P = 0.002) showed a statistically significant association with SIB. Patients with SIB had a greater probability of being selected for deep brain stimulation (DBS) therapy by the treating clinician (P = 0.01).
conclusionsSIB is observed in about 17% of patients with TS. The presence of complex motor tics, OCD and greater severity of tics was related to the presence of SIB.
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