Evidence map›Paper›PMID 34596736›Full record

ArticleInternational journal of colorectal disease2022

Incidence and predictors of brain metastasis in colorectal cancer patients.

Elishia Thompson, Shoujit Banerjee, Sierra Thompson, Ryan Silva, Andrew Muse, Hina Arif-Tiwari, Aron J Scott, Valentine Nfonsam

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Article in International journal of colorectal disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elishia ThompsonDepartment of Surgery, University of Arizona Medical Center, Tucson, USA.
Shoujit BanerjeeDepartment of Surgery, University of Arizona Medical Center, Tucson, USA.
Sierra ThompsonDepartment of Surgery, University of Arizona Medical Center, Tucson, USA.
Ryan SilvaDepartment of Surgery, University of Arizona Medical Center, Tucson, USA.
Andrew MuseDepartment of Surgery, University of Arizona Medical Center, Tucson, USA.
Hina Arif-TiwariDepartment of Medical Imaging, University of Arizona Medical Center, Tucson, USA.
Aron J ScottDepartment of Medicine, University of Arizona Medical Center, Tucson, USA.
Valentine NfonsamDepartment of Surgery, University of Arizona Medical Center, Tucson, USA. vnfonsam@surgery.arizona.edu.ORCID http://orcid.org/0000-0002-1213-8053

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeBrain metastasis (BM) in colorectal cancer patients is rare and is associated with dismal outcomes. Our study aims to evaluate the incidence and predictors of BM in patients with colorectal cancer.

methodsWe performed a retrospective analysis (2010-2017) of patients with a primary diagnosis of colorectal cancer (CRC). Patients were stratified into two groups (BM vs. No-BM). Outcome measures were the incidence and predictors of BM. Multivariate logistic regression analysis was performed.

resultsA total of 230,806 patients were analyzed. A total of 0.30% (n = 691) of the patients were found to have BM. On multivariate logistics regression, bone (OR: 5.39 [3.36-8.65], p < 0.001), lung (OR: 3.75 [2.67-5.28], < 0.001), and distant node metastasis (OR: 32.75 [20.47-52.41], p < 0.001) were independent predictors of BM.

conclusionOur study supports the low incidence of brain metastasis in patients with colorectal cancer. A unique set of characteristics is identified to confer an increased risk of brain metastases.

Indexed as

Brain NeoplasmsColorectal NeoplasmsHumansIncidencePrognosisRetrospective StudiesBrain metastasisColorectal cancerIncidencePredictors

Identifiers

PMID34596736

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.