SynthesisDer Anaesthesist2022
[Update on PONV-What is new in prophylaxis and treatment of postoperative nausea and vomiting? : Summary of recent consensus recommendations and Cochrane reviews on prophylaxis and treatment of postoperative nausea and vomiting].
Synthesis in Der Anaesthesist, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 5 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- Pooled it
- The efficacy of transcutaneous electrical acupoint stimulation on postoperative nausea and vomiting after laparoscopic surgery: a meta-analysis of randomized controlled trials.Frontiers in medicine · 2026Pooled it
- Nausea and vomiting as adverse events of oliceridine: a systematic review and meta-analysis of randomized controlled trials.Frontiers in pharmacology · 2026Pooled it
- Efficacy of paravertebral block on postoperative nausea and vomiting: a meta-analysis of randomized controlled trial.BMC anesthesiology · 2025Pooled it
- The preventive effect of dexmedetomidine on anesthesia complications in strabismus surgery: a systematic review and meta-analysis.BMC anesthesiology · 2023Pooled it
- Trial
- Fosaprepitant versus Ondansetron for Preventing Postoperative Nausea and Vomiting After Video-Assisted Thoracoscopic Lung Resection: A Randomized Controlled Clinical Trial.Drug design, development and therapy · 2026Trial
- Promethazine for nausea and vomiting prevention after gynaecological laparoscopic surgery: A randomized controlled trial.Scientific reports · 2025Trial
- Trial
- Trial
- Desflurane combined with ciprofol or esketamine improves postoperative symptoms without compromising early neurocognitive recovery after intracranial aneurysm endovascular coiling.Frontiers in medicine · 2026Article
- Construction and Validation of a Risk Prediction Model for Postoperative Nausea and Vomiting in Patients with Liver Cancer.Journal of hepatocellular carcinoma · 2026Article
- Adequacy of Anesthesia Guidance Combined with Peribulbar Blocks Shows Potential Benefit in High-Risk PONV Patients Undergoing Vitreoretinal Surgeries.Journal of clinical medicine · 2025Article
- Analysis of ambulatory gynecological laparoscopy in Southwestern China and predictors of discharge: a retrospective cohort : Ambulatory surgery delayed discharge analysis.Surgical endoscopy · 2025Article
- Adverse Events Following Vitreoretinal Surgeries Under Adequacy of Anesthesia with Combined Paracetamol/Metamizole-Additional Report.Journal of clinical medicine · 2025Article
- Effects of total intravenous anaesthesia versus inhalation anaesthesia on gastrointestinal function recovery after laparoscopic hysterectomy: A randomised controlled trial.Indian journal of anaesthesia · 2025Article
- Important aspects of the multimodal perioperative management in gynecology.Archives of gynecology and obstetrics · 2025Review
- A Review of Non-Cardiac Complications of General Anesthesia: The Current State of Knowledge.Medical science monitor : international medical journal of experimental and clinical research · 2025Review
- Comparison of aprepitant versus ondansetron for prevention of postoperative nausea and vomiting: A systematic review and meta-analysis with trial sequential analysis.Indian journal of anaesthesia · 2024Article
- [Remimazolam-Update on basic pharmacologic principles and clinical potential].Die Anaesthesiologie · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The prophylaxis and treatment of postoperative pain to enhance patient comfort has been a primary goal of anesthesiologists for the last decades; however, avoiding postoperative nausea and vomiting (PONV) is, from a patient's perspective, a highly relevant and equally important goal of anesthesia. Recent consensus-based guidelines suggest the assessment of risk factors including female gender, postoperative opioid administration, non-smoking status, a history of PONV or motion sickness, young patient age, longer duration of anesthesia, volatile anesthetics and the type of surgery and reducing the patient's baseline risk (e.g. through the use of regional anesthesia and administration of non-opioid analgesics as part of a multimodal approach). In general, a liberal PONV prophylaxis is encouraged for adult patients and children, which should also be administered when no risk assessment is made. The basis for every adult patient should be a standard prophylaxis with two antiemetics, such as dexamethasone in combination with a 5-HT
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.