Evidence map›Paper›PMID 34596594›Full record

ArticleSaudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association

Prevalence, severity and associated factors of restless leg syndrome in inflammatory bowel disease patients.

Othman R AlHarbi, Ahmad Bahammam, Awad H Olaish, Nahla A Azzam, Abdulrahman A Aljebreen, Majid A Almadi, Suhail A Alsaleh

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Othman R AlHarbiDepartment of Medicine, Division of Gastroenterology, College of Medicine, King Khalid University Hospital, King Saud University Medical City, King Saud University, Riyadh, Saudi Arabia.
Ahmad BahammamThe University Sleep Disorders Center, College of Medicine, King Saud University Medical City, Riyadh, Saudi Arabia.
Awad H OlaishThe University Sleep Disorders Center, College of Medicine, King Saud University Medical City, Riyadh, Saudi Arabia.
Nahla A AzzamDepartment of Medicine, Division of Gastroenterology, College of Medicine, King Khalid University Hospital, King Saud University Medical City, King Saud University, Riyadh, Saudi Arabia.
Abdulrahman A AljebreenDepartment of Medicine, Division of Gastroenterology, College of Medicine, King Khalid University Hospital, King Saud University Medical City, King Saud University, Riyadh, Saudi Arabia.
Majid A AlmadiDepartment of Medicine, Division of Gastroenterology, College of Medicine, King Khalid University Hospital, King Saud University Medical City, King Saud University, Riyadh, Saudi Arabia; Division of Gastroenterology, the McGill University Health Center, Montréal General Hospital, McGill University, Montréal, Canada.
Suhail A AlsalehDepartment of Pediatrics, Division of Pediatric Respiratory Medicine, The Hospital for Sick Children, University of Toronto, Canada.
King Saud University · SAKing Khalid University Hospital · SAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe association between restless leg syndrome (RLS) and inflammatory bowel disease (IBD) has often been an under-investigated and clinically misdiagnosed entity. An emphasis should be made on the severity and associated factors, as the prevalence of both entities is on the rise globally. In this study we aimed to investigate the prevalence, severity and associated risk factors of RLS in patients with IBD.

methodsA multi-center, prospective cross-sectional study was conducted with age and gender matched controls in the ratio of 1:3. Cases of IBD were confirmed according to European Crohns and Colitis Organization guidelines. The study recruited 377 cases and 1131 age and gender-matched controls. RLS severity and prevalence was determined using a validated International Restless Legs Syndrome Study Group questionnaire. The anthropometric and blood biochemical measurements were retrieved from the patient's medical records. Associated factors were analyzed by regression analysis.

resultsThe prevalence of RLS in patients with IBD and non-IBD control groups was 21.5% and 9.7%, respectively (P = 0.001). The severity index of RLS symptoms in all the three categories of mild, moderate and severe RLS was higher in the IBD group (P = 0.001). Obesity (BMI >30 Kg/m

conclusionPrevalence and severity of RLS was higher in patients with IBD. The risk factors for RLS in IBD include increasing age, obesity, higher TSH, and lower hemoglobin.

Indexed as

ColitisInflammatory Bowel DiseasesRestless Legs SyndromeCross-Sectional StudiesHumansMiddle AgedPrevalenceProspective StudiesSeverity of Illness IndexInflammatory bowel diseaseprevalencerestless leg syndromerisk factorsSaudi Arabia

Identifiers

PMID34596594
PMCPMC8656329
OpenAlexW3203309739

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.