Evidence map›Paper›PMID 34596443›Full record

ArticleASN neuro

Forelimb Motor Skills Deficits Following Thoracic Spinal Cord Injury: Underlying Dopaminergic and Neural Oscillatory Changes in Rat Primary Motor Cortex.

Omid Salimi, Hamid Soltani Zangbar, Soheila Hajizadeh Shadiabad, Meysam Ghorbani, Tahereh Ghadiri, Abbas Ebrahimi Kalan, Hasan Kheyrkhah, Parviz Shahabi

Open access · goldAbstract read
In one paragraph

Article in ASN neuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Omid SalimiNeurosciences Research Center, 226716Tabriz University of Medical Sciences, Tabriz, Iran.
Hamid Soltani ZangbarDepartment of Neuroscience and Cognition, Faculty of Advanced Medical Sciences, 226716Tabriz University of Medical Sciences, Tabriz, Iran.
Soheila Hajizadeh ShadiabadDivision of Cognitive Neuroscience, Faculty of Education and Psychology, 226716University of Tabriz, Tabriz, Iran.
Meysam GhorbaniNeurosciences Research Center, 226716Tabriz University of Medical Sciences, Tabriz, Iran.
Tahereh GhadiriDepartment of Neuroscience and Cognition, Faculty of Advanced Medical Sciences, 226716Tabriz University of Medical Sciences, Tabriz, Iran.
Abbas Ebrahimi KalanDepartment of Neuroscience and Cognition, Faculty of Advanced Medical Sciences, 226716Tabriz University of Medical Sciences, Tabriz, Iran.
Hasan KheyrkhahDepartment of Physiology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.ORCID 0000-0001-9962-5761
Parviz ShahabiNeurosciences Research Center, 226716Tabriz University of Medical Sciences, Tabriz, Iran.ORCID 0000-0001-5594-5544
Tabriz University of Medical Sciences · IRIsfahan University of Medical Sciences · IRUniversity of Tabriz · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The loss of spinal sensorimotor pathways following spinal cord injury (SCI) can induce retrograde neurodegeneration in the primary motor cortex (M1). However, the effect of thoracic SCI on forelimb motor skills has not been studied clearly. So, herein we aimed to examine the effects of the thoracic SCI model on forelimb motor skills learning, parallel with dopaminergic and oscillatory changes in hindlimb and forelimb areas (HLA and FLA) of M1 in rats. Male Wistar rats were randomly subjected to laminectomy (Control) or contusion SCI at the thoracic (T10) level. Oscillatory activity and motor skills performance were evaluated for six consecutive days using local field potential (LFP) recording and skilled forelimb reaching task, respectively. Dopamine (DA) levels and expression of dopamine receptors (D

Indexed as

Motor CortexSpinal Cord InjuriesAnimalsDopamineForelimbMaleMotor SkillsRatsRats, WistarRecovery of FunctionSpinal CordDopaminedeltadopamineFLAforelimb motor skillsfunctiongammaM1motor cortexoscillationsspinal cord injurytheta

Identifiers

PMID34596443
PMCPMC8495518
OpenAlexW3204046033

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.