ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2022
Changing Patterns of Bloodstream Infections in the Community and Acute Care Across 2 Coronavirus Disease 2019 Epidemic Waves: A Retrospective Analysis Using Data Linkage.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
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Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Global Burden of Bloodstream Infections in COVID-19: Prevalence, Antimicrobial Resistance, and Mortality Risk.Viruses · 2025Pooled it
- Incidence and Outcomes of Bloodstream Infections in Critically Ill Patients with COVID-19: A Nationwide Multicenter Study in South Korea.Yonsei medical journal · 2026Observational
- Article
- A Prediction Score Versus Procalcitonin and Presepsin for Predicting Bacteremia in the Emergency Department: A Single-Center Retrospective Cohort Study.Diagnostics (Basel, Switzerland) · 2026Article
- The Association Between Antibiotic Use and the Incidence of Third-Generation Cephalosporin-Resistance inAntibiotics (Basel, Switzerland) · 2026Article
- COVID-19 impact on AMR: a rapid scoping review, equity analysis and evidence gap map study.BMJ global health · 2025Article
- Secondary Bacterial Infections in Critically Ill COVID-19 Patients Admitted in the Intensive Care Unit of a Tertiary Hospital in Romania.Journal of clinical medicine · 2024Article
- Microbiology of bloodstream infections in Ontario, Canada during COVID-19 pandemic.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2024Article
- Risk factors for healthcare-associated infections and their relationship with waves of the COVID-19 pandemic in an intensive care unit: a nested case-control study.Einstein (Sao Paulo, Brazil) · 2024Article
- The impact of the COVID-19 pandemic on blood culture practices and bloodstream infections.Microbiology spectrum · 2023Article
- Article
- Evaluation of Blood Cultures from SARS-CoV-2-Positive and Negative Adult Patients.Healthcare (Basel, Switzerland) · 2023Article
- Effect of Wearing Personal Protective Equipment (PPE) for COVID-19 Treatment on Blood Culture Contamination: Implication for Optimal PPE Strategies.Journal of Korean medical science · 2023Article
- Article
- Collateral impacts of pandemic COVID-19 drive the nosocomial spread of antibiotic resistance: A modelling study.PLoS medicine · 2023Article
- Incremental costs of hospital-acquired infections in COVID-19 patients in an adult intensive care unit of a tertiary hospital from a low-resource setting.Antimicrobial resistance and infection control · 2023Article
- A multicenter evaluation of antibacterial use in hospitalized patients through the SARS-Cov-2 pandemic waves.BMC infectious diseases · 2023Article
- Trends inAntibiotics (Basel, Switzerland) · 2023Review
- Evaluation of the implementation of WHO infection prevention and control core components in Turkish health care facilities: results from a WHO infection prevention and control assessment framework (IPCAF)-based survey.Antimicrobial resistance and infection control · 2023Article
- A Tale of Two Pandemics: Antimicrobial Resistance Patterns ofAntibiotics (Basel, Switzerland) · 2023Article
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11 authors.
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Abstract
backgroundWe examined community- and hospital-acquired bloodstream infections (BSIs) in coronavirus disease 2019 (COVID-19) and non-COVID-19 patients across 2 epidemic waves.
methodsWe analyzed blood cultures of patients presenting to a London hospital group between January 2020 and February 2021. We reported BSI incidence, changes in sampling, case mix, healthcare capacity, and COVID-19 variants.
resultsWe identified 1047 BSIs from 34 044 blood cultures, including 653 (62.4%) community-acquired and 394 (37.6%) hospital-acquired. Important pattern changes were seen. Community-acquired Escherichia coli BSIs remained below prepandemic level during COVID-19 waves, but peaked following lockdown easing in May 2020, deviating from the historical trend of peaking in August. The hospital-acquired BSI rate was 100.4 per 100 000 patient-days across the pandemic, increasing to 132.3 during the first wave and 190.9 during the second, with significant increase in elective inpatients. Patients with a hospital-acquired BSI, including those without COVID-19, experienced 20.2 excess days of hospital stay and 26.7% higher mortality, higher than reported in prepandemic literature. In intensive care, the BSI rate was 421.0 per 100 000 intensive care unit patient-days during the second wave, compared to 101.3 pre-COVID-19. The BSI incidence in those infected with the severe acute respiratory syndrome coronavirus 2 Alpha variant was similar to that seen with earlier variants.
conclusionsThe pandemic have impacted the patterns of community- and hospital-acquired BSIs, in COVID-19 and non-COVID-19 patients. Factors driving the patterns are complex. Infection surveillance needs to consider key aspects of pandemic response and changes in healthcare practice.
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