Evidence map›Paper›PMID 34596013›Full record

ArticleJournal of medical microbiology2021

2-Alkyl-4-quinolone quorum sensing molecules are biomarkers for culture-independent

Nur Masirah M Zain, Karmel Webb, Iain Stewart, Nigel Halliday, David A Barrett, Edward F Nash, Joanna L Whitehouse, David Honeybourne, Alan R Smyth, Douglas L Forrester and 6 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medical microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. A year in review: Real world evidence, functional monitoring and emerging therapeutics in 2021.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2022
    Review
  3. Frontiers in microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 2 countries.

Nur Masirah M ZainInstitute of Pharmaceutical Science, King's College London, London, UK.
Karmel WebbNottingham NIHR Biomedical Research Centre, Nottingham MRC Molecular Pathology Node, Nottingham, UK.
Iain StewartNottingham NIHR Biomedical Research Centre, Nottingham MRC Molecular Pathology Node, Nottingham, UK.
Nigel HallidayNational Biofilms Innovation Centre, University of Nottingham Biodiscovery Institute, School of Life Sciences, University of Nottingham, Nottingham, UK.
David A BarrettCentre for Analytical Bioscience, Division of Advanced Materials and Healthcare Technologies, School of Pharmacy, University of Nottingham, Nottingham, UK.
Edward F NashWest Midlands Adult CF Centre, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Joanna L WhitehouseWest Midlands Adult CF Centre, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
David HoneybourneWest Midlands Adult CF Centre, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Alan R SmythNottingham NIHR Biomedical Research Centre, Nottingham MRC Molecular Pathology Node, Nottingham, UK.
Douglas L ForresterUniversity of Queensland, Northside Clinical Unit, Brisbane, Queensland, Australia.
Alan J KnoxDivision of Respiratory Medicine, University of Nottingham, City Hospital Campus, Nottingham, UK.
Paul WilliamsNational Biofilms Innovation Centre, University of Nottingham Biodiscovery Institute, School of Life Sciences, University of Nottingham, Nottingham, UK.
Andrew FogartyNottingham NIHR Biomedical Research Centre, Nottingham MRC Molecular Pathology Node, Nottingham, UK.
Miguel CámaraNational Biofilms Innovation Centre, University of Nottingham Biodiscovery Institute, School of Life Sciences, University of Nottingham, Nottingham, UK.
Kenneth D BruceInstitute of Pharmaceutical Science, King's College London, London, UK.
Helen L BarrWolfson Cystic Fibrosis Centre, Department of Respiratory Medicine, Nottingham University Hospitals NHS Trust, Nottingham, UK.
University of Nottingham · GBUniversity Hospitals Birmingham NHS Foundation Trust · GBKing's College London · GBNottingham Biomedical Research Centre · GBNottingham University Hospitals NHS Trust · GBThe University of Queensland · AU

Funding

Medical Research Council G0801558Medical Research Council MR/N005953/1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Quorum Sensing4-QuinolonesAdolescentAdultBacterial LoadBiomarkersCystic FibrosisFemaleHumansMaleMiddle AgedPseudomonas aeruginosaPseudomonas InfectionsReal-Time Polymerase Chain ReactionSputumYoung Adult4-QuinolonesBiomarkersalkyl-quinolonescystic fibrosisPMA-qPCRPseudomonas aeruginosaquorum sensing molecules

Identifiers

PMID34596013
PMCPMC8604169
OpenAlexW3204471479

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.