Evidence map›Paper›PMID 34595730›Full record

SynthesisActa neurologica Belgica2022

Skull base hemangiopericytomas.

Samuel Tobias, Shady Jahshan, Yuval Grober, Jean F Soustiel

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Acta neurologica Belgica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Samuel TobiasDepartment of Neurosurgery, Galilee Medical Center, Naharia and The Azrieli Faculty of Medicine, Bar Ilan University, POB 21, 2210001, Zafed, Naharia, Israel.
Shady Jahshan *Department of Neurosurgery, Galilee Medical Center, Naharia and The Azrieli Faculty of Medicine, Bar Ilan University, POB 21, 2210001, Zafed, Naharia, Israel.
Yuval GroberDepartment of Neurosurgery, Galilee Medical Center, Naharia and The Azrieli Faculty of Medicine, Bar Ilan University, POB 21, 2210001, Zafed, Naharia, Israel.
Jean F SoustielDepartment of Neurosurgery, Galilee Medical Center, Naharia and The Azrieli Faculty of Medicine, Bar Ilan University, POB 21, 2210001, Zafed, Naharia, Israel. jeans@gmc.gov.il.ORCID http://orcid.org/0000-0001-8444-2372
Bar-Ilan University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo retrospectively evaluate the clinical outcome of six patients with skull base hemangiopericytomas (HPCs) and that of a cohort of 37 similar patients identified by a systematic review of the literature.

methodsThe series constitutes of three men and three women with newly diagnosed skull base HPC who underwent multimodal treatment including surgery, external beam radiotherapy (EBRT) and pre-operative embolization. Furthermore, a systematic review off the literature identified 37 reports of primarily intracranial skull base HPCs.

resultsFour patients had a gross total resection (GTR) and two patients had a near total resection. Five patients were referred for adjuvant EBRT with a survival ranging from 15 to 47 months. All patients had an excellent outcome and resumed their previous activities. Literature review identified 37 additional patients with skull base HPC. Altogether, tumors were unevenly distributed above and below tentorium. GTR was achieved in half the patients, and 72.1% were referred to EBRT. Out of 37 reported patients in the literature, survival longer than 1 year was described in only 24. Within the combined cohort including the present series, survival was 83.6 months.

conclusionsThe present series shows that a radical resection of HPC can be achieved under the difficult anatomical conditions of skull base surgery. Pre-operative arterial embolization may be instrumental to maintain a clear visual field and prevent excessive blood loss. Finally, the results of the present cohort suggest that EBRT may be useful for local growth control, as an effective palliative measure for skull base HPCs.

Indexed as

HemangiopericytomaCombined Modality TherapyFemaleHumansMaleNeurosurgical ProceduresRetrospective StudiesSkull BaseTreatment OutcomeHemangiopericytomaOncologySkull baseSolitary-fibrous tumor

Identifiers

PMID34595730
OpenAlexW3204740157

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.