Evidence map›Paper›PMID 34595699›Full record

ArticleEnvironmental science and pollution research international2022

Bioactivity and safety evaluations of Cupressus sempervirens essential oil, its nanoemulsion and main terpenes against Culex quinquefasciatus Say.

Abdulrhman A Almadiy, Gomah E Nenaah

Abstract read
PubMed Publisher
In one paragraph

Article in Environmental science and pollution research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Integrative Toxicology Profiling ofFood science & nutrition · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Biological Activity ofPlants (Basel, Switzerland) · 2023
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Abdulrhman A AlmadiyDepartment of Biology, Faculty of Arts and Sciences, Najran University, Najran, 1988, Saudi Arabia.
Gomah E NenaahDepartment of Biology, Faculty of Arts and Sciences, Najran University, Najran, 1988, Saudi Arabia. dr_nenaah1972@yahoo.com.ORCID http://orcid.org/0000-0002-0541-6254
Kafrelsheikh University · EGNajran University · SA

Funding

deputy for the research and innovation, ministry of education, kingdom of saudi arabia NU/IFC/ENT/01/003
6 · The paper itself

Abstract

The essential oil (EO) of Cupressus sempervirens was obtained by hydrodistillation and analysed using gas chromatography-flame ionization detection (GC-FID) and gas chromatography-mass spectrometry (GC-MS). Two monoterpenes, α-pinene (49.1%) and δ-3-carene (21.4%), and one sesquiterpene hydrocarbon, α-cedrol (5.1%), were isolated as the EO major terpenes. An oil-in-water nanoemulsion (particle size 71.2 nm) was produced from the EO through a low-energy method. The EO, its nanoemulsion and its main constituents showed mosquitocidal and biochemical effects against Culex quinquefasciatus Say, the common vector of lymphatic filariasis parasites. All treatments showed dose-dependent bioactivity, and adults were more susceptible to the EO products than the larvae. The nanoemulsion showed superior activity, followed by the crude EO and α-cedrol. At 40 μg/ml, the nanoemulsion caused 100% larval mortality, while the EO and α-cedrol required twice this concentration to achieve the same larval mortality. The LC

Indexed as

AedesAnophelesCulexCupressusInsecticidesOils, VolatileAcetylcholinesteraseAnimalsGas Chromatography-Mass SpectrometryLarvaMosquito VectorsPlant LeavesTerpenesAcetylcholinesteraseInsecticidesOils, VolatileTerpenesBioactivityCulex quinquefasciatusCupressus sempervirensEssential oilMain terpenesNanoemulsionSafety evaluation

Identifiers

PMID34595699
OpenAlexW3204086627

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.