Evidence map›Paper›PMID 34595589›Full record

ArticleMarine biotechnology (New York, N.Y.)2021

Genome-Wide Characterization of Aquaporins (aqps) in Lateolabrax maculatus: Evolution and Expression Patterns During Freshwater Acclimation.

Xiaoyan Zhang, Peng Yu, Haishen Wen, Xin Qi, Yuan Tian, Kaiqiang Zhang, Qiang Fu, Yun Li, Chao Li

Abstract read
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In one paragraph

Article in Marine biotechnology (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. RNA-Seq Reveals Adaptation Strategy in Grass Carp (International journal of molecular sciences · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Xiaoyan ZhangSchool of Marine Science and Engineering, Qingdao Agricultural University, Qingdao, 266109, China.
Peng YuThe Key Laboratory of Mariculture, Ministry of Education, Ocean University of China), Ocean University of China, Qingdao, 266003, China.
Haishen WenThe Key Laboratory of Mariculture, Ministry of Education, Ocean University of China), Ocean University of China, Qingdao, 266003, China.
Xin QiThe Key Laboratory of Mariculture, Ministry of Education, Ocean University of China), Ocean University of China, Qingdao, 266003, China.
Yuan TianThe Key Laboratory of Mariculture, Ministry of Education, Ocean University of China), Ocean University of China, Qingdao, 266003, China.
Kaiqiang ZhangThe Key Laboratory of Mariculture, Ministry of Education, Ocean University of China), Ocean University of China, Qingdao, 266003, China.
Qiang FuSchool of Marine Science and Engineering, Qingdao Agricultural University, Qingdao, 266109, China.
Yun LiThe Key Laboratory of Mariculture, Ministry of Education, Ocean University of China), Ocean University of China, Qingdao, 266003, China.
Chao LiSchool of Marine Science and Engineering, Qingdao Agricultural University, Qingdao, 266109, China. chaoli@qau.edu.cn.ORCID http://orcid.org/0000-0002-1950-0190
Ocean University of China · CNQingdao Agricultural University · CN

Funding

agriculture research system of china CARS-47
6 · The paper itself

Abstract

Aquaporin (aqp) proteins are a group of small integral membrane proteins that play crucial roles as pore channels for the transport of water and other small solutes across the cell membrane. In our study, we identified 17 aqp genes from the spotted sea bass (Lateolabrax maculatus) genomic database. Gene organization, motif distribution, and selection pressure analyses were performed to investigate their evolutionary characteristics. The aqp mRNA displayed tissue-specific expression pattern in ten selected tissues of healthy spotted sea bass. To investigate the potential involvement of spotted sea bass aqps in osmoregulation, the expression profiles of aqp genes in gills were examined during freshwater (FW) acclimation using qRT-PCR. The mRNA level of aqp3a was dramatically induced during 1-3 day of the FW transition period (77-fold and 15-fold upregulated on 1 day and 3 day than in the control group), indicating that aqp3a may play an important hypo-osmoregulatory role in spotted sea bass. In addition, the expression levels of aqp1aa, aqp1ab, aqp3b, aqp7, and aqp9b increased to various degrees at 1 day after transferring to FW, suggesting their potential involvement in the FW acclimation process. Our study provides a valuable foundation for future studies aimed at uncovering the specific roles of aqp genes during salinity acclimation in spotted sea bass and other teleost species.

Indexed as

AcclimatizationAnimalsAquaporinsBassFish ProteinsFresh WaterGene Expression RegulationGenome-Wide Association StudyOsmoregulationRNA, MessengerSalinityAquaporinsFish ProteinsRNA, MessengerAquaporin (aqp) genesExpressionGillLateolabrax maculatusOsmoregulation

Identifiers

PMID34595589
OpenAlexW3202494198

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.