SynthesisPediatric nephrology (Berlin, Germany)2022
Risk factors for acute kidney injury after pediatric cardiac surgery: a meta-analysis.
Synthesis in Pediatric nephrology (Berlin, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 6 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- Machine learning model predicts acute kidney injury in pediatric patients after cardiac surgery: a systematic review and meta-analysis.BMC nephrology · 2026Pooled it
- Perioperative Monitoring of Regional Oxygen Saturation in Congenital Heart Disease: Systematic Review of Literature up to 2023.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2026Pooled it
- Machine learning models for predicting postoperative acute kidney injury in pediatric cardiac surgery: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2026Pooled it
- Biomarkers of acute kidney injury after pediatric cardiac surgery: a meta-analysis of diagnostic test accuracy.European journal of pediatrics · 2022Pooled it
- Meta-Resolve of Risk Factors for Nosocomial Infection in Patients Undergoing Thoracic Surgery.Contrast media & molecular imaging · 2022Pooled it
- Dexmedetomidine and acute kidney injury following cardiac surgery in pediatric patients-An updated systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2022Pooled it
- Population Pharmacokinetics and Target Attainment of Allopurinol and Oxypurinol Before, During, and After Cardiac Surgery with Cardiopulmonary Bypass in Neonates with Critical Congenital Heart Disease.Clinical pharmacokinetics · 2024Trial
- The incidence and risk factors associated with severe acute kidney injury and operative mortality in neonates following cardiac surgery: a single-center experience.Pediatric nephrology (Berlin, Germany) · 2026Article
- Incidence and factors associated with acute kidney injury after the bidirectional Glenn procedure in patients with functional single ventricle.European journal of pediatrics · 2026Article
- Using health systems evidence to study and predict long-term outcomes of childhood acute kidney injury.Pediatric nephrology (Berlin, Germany) · 2026Article
- Acute Kidney Injury After Pediatric Heart Transplant: The Impact of Intraoperative Hemodynamics Using High-Fidelity Data.Pediatric cardiology · 2026Article
- Quality Assessment in Paediatric Cardiology: Experiences from Leveraging a Clinical Data Warehouse.Life (Basel, Switzerland) · 2026Article
- Research progress on biomarkers for acute kidney injury in children.Pediatric nephrology (Berlin, Germany) · 2026Review
- Intraoperative renal and cerebral tissue oxygen saturation measurements to predict postoperative acute kidney injury in pediatric cardiac surgery: a prospective observational study.Journal of clinical monitoring and computing · 2026Observational
- Observational
- Development and Validation of an Interpretable Model for Predicting Postoperative Hyperlactatemia in Young Children Following Congenital Heart Surgery.Journal of clinical medicine · 2026Article
- Modifiable risk factors in type 1 cardiorenal syndrome in children with congenital heart disease: a retrospective cohort study.BMC cardiovascular disorders · 2026Article
- A novel nomogram for predicting early postoperative cerebral desaturation events after congenital heart surgery.Frontiers in surgery · 2026Article
- Iron-related protein in prediction of acute kidney injury in the pediatric population after cardiac surgery.Journal of cardiothoracic surgery · 2025Article
- Renal Replacement Therapy in Pediatric Cardiac Intensive Care: A Retrospective Analysis of Modalities, Outcomes, and Prognostic Factors.Journal of clinical medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCardiac surgery-associated acute kidney injury (AKI) is associated with increased morbidity and mortality in both adults and children.
objectivesThis study aimed to identify clinical risk factors for AKI following cardiac surgery in the pediatric population. DATA SOURCES: PubMed/MEDLINE, Embase, Scopus, and reference lists of relevant articles were searched for studies published by August 2020. STUDY ELIGIBILITY CRITERIA: Studies were included if (1) the population consisted of pediatric patients (< 18 years old), (2) patients underwent cardiac surgery, (3) risk factors were compared between patients who developed AKI and those who did not, and (4) studies were prospective or retrospective observational studies or randomized controlled trials. PARTICIPANTS AND
interventionsChildren undergoing pediatric cardiac surgery. STUDY APPRAISAL AND SYNTHESIS
methodsRandom-effects meta-analysis was performed, comparing potential risk factors between pediatric patients who developed CS-AKI and those who did not.
resultsSixty-one publications including a total of 19,680 participants (AKI: 7257 participants; no AKI: 12,423 participants) were included from studies published between 2008 and 2020. The pooled estimated incidence of AKI was 34.3% (95% confidence interval 30.0-38.8%, I LIMITATIONS: Results are limited by heterogeneity and potential residual confounding. CONCLUSIONS AND IMPLICATIONS OF KEY
findingsOur meta-analysis identified clinical risk factors that are associated with AKI in children undergoing cardiac surgery. This might help clinicians anticipate and manage more carefully this population and implement standardized preventive strategies. SYSTEMATIC REVIEW REGISTRATION NUMBER: CRD42021262699. A higher resolution version of the Graphical abstract is available as Supplementary information.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.