Evidence map›Paper›PMID 34595436›Full record

ArticleClinical hematology international2020

Summary of Scientific and Statistical Methods, Study Endpoints and Definitions for Observational and Registry-Based Studies in Hematopoietic Cell Transplantation.

Abraham S Kanate, Arnon Nagler, Bipin Savani

Open access · hybridAbstract read
In one paragraph

Article in Clinical hematology international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed, 1 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 1 synthesis or guideline pooled it, 95 citations in OpenAlex.

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8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Abraham S KanateHematopoietic Malignancy and Cellular Therapy, West Virginia University Cancer Institute, Morgantown, WV, USA.
Arnon NaglerChaim Sheba Medical Center, Tel Aviv University, Tel-Hashomer, Ramat Gan, Israel.
Bipin SavaniDepartment of Hematology-Oncology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Vanderbilt University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the increasingly strict word/character restrictions enforced by most scientific publications, we identified a need for a master document illustrating the "Scientific Methods" that may be applicable to the majority of observational and registry-based studies in hematopoietic cell transplantation (HCT). The purpose of this study is to serve as a reference document that describes the data source, study endpoints and statistical analyses utilized most commonly in retrospective studies in HCT. To this end we compile, define and reference the methodology commonly used in HCT research. While it is recognized that the scientific methodology may periodically require updates due to the evolving landscape of transplant research, such as newer study endpoints and statistical methods, this manuscript describes frequently used methodologies.

Indexed as

Hematopoietic cell transplantationScientific methodsStudy definitionsStudy endpoints

Identifiers

PMID34595436
PMCPMC8432337
OpenAlexW2996146575

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.