Evidence map›Paper›PMID 34595434›Full record

ArticleClinical hematology international2019

Use of Biosimilar Granulocyte Colony-Stimulating Factor for Mobilization in Autologous and Allogeneic Hematopoietic Stem Cell Transplantation.

Dwight D Eplin, Anna D Jackson, Austin M Smith, Brent Salvig, Wichai Chinratanalab, Bipin N Savani

Open access · hybridAbstract read
In one paragraph

Article in Clinical hematology international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 84% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Dwight D EplinVA Tennessee Valley Healthcare System; Nashville, Tennessee.
Anna D JacksonVA Tennessee Valley Healthcare System; Nashville, Tennessee.
Austin M SmithVA Tennessee Valley Healthcare System; Nashville, Tennessee.
Brent SalvigVA Tennessee Valley Healthcare System; Nashville, Tennessee.
Wichai ChinratanalabVA Tennessee Valley Healthcare System; Nashville, Tennessee.
Bipin N SavaniVA Tennessee Valley Healthcare System; Nashville, Tennessee.
VA Tennessee Valley Healthcare System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The biologic medication filgrastim is approved by the Food and Drug Administration (FDA) to mobilize hematopoietic progenitor cells (HPCs) for collection by leukapheresis for autologous hematopoietic stem cell transplant (HSCT). The FDA-approved biologic tbo-filgrastim is currently used off-label for this indication in both autologous and allogeneic HSCT at the Tennessee Valley Healthcare System. The purpose of this review is to compare the efficacy of filgrastim and tbo-filgrastim for this indication. The primary outcomes were the proportion of autologous patients and allogeneic donors with a CD34+ count ≥15 × 10

Indexed as

BiosimilarFilgrastimGranulocyte colony-stimulating factorHematopoietic stem cell transplantationStem cell mobilizationTbo-filgrastim

Identifiers

PMID34595434
PMCPMC8432370
OpenAlexW2980344986

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.