Evidence map›Paper›PMID 34595395›Full record

ArticleAccess microbiology2021

Using genome comparisons of wild-type and resistant mutants of

Feng Long, Chen-Yi Cheung, William B Whitman, Gregory M Cook, Ron S Ronimus

Open access · goldAbstract read
In one paragraph

Article in Access microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Feng LongDepartment of Microbiology, University of Georgia, Athens, Georgia, USA.
Chen-Yi CheungDepartment of Microbiology and Immunology, University of Otago, Dunedin, New Zealand.ORCID https://orcid.org/0000-0002-5850-0919
William B WhitmanDepartment of Microbiology, University of Georgia, Athens, Georgia, USA.ORCID https://orcid.org/0000-0003-1229-0423
Gregory M CookDepartment of Microbiology and Immunology, University of Otago, Dunedin, New Zealand.
Ron S RonimusRumen Microbiology, AgResearch Ltd., Palmerston North, New Zealand.
University of Otago · NZAgResearch · NZCleveland Clinic · USUniversity of Georgia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methane emissions from enteric fermentation in the ruminant digestive system generated by methanogenic archaea are a significant contributor to anthropogenic greenhouse gas emissions. Additionally, methane produced as an end-product of enteric fermentation is an energy loss from digested feed. To control the methane emissions from ruminants, extensive research in the last decades has been focused on developing viable enteric methane mitigation practices, particularly, using methanogen-specific inhibitors. We report here the utilization of two known inhibitors of methanogenic archaea, neomycin and chloroform, together with a recently identified inhibitor, echinomycin, to produce resistant mutants of

Indexed as

chloroformechinomycinmethanogenmethanogen-specific inhibitorsneomycinrumenwhole-genome sequencing

Identifiers

PMID34595395
PMCPMC8479958
OpenAlexW3202698207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.