Evidence map›Paper›PMID 34595223›Full record

ArticleFrontiers in cardiovascular medicine2021

Epicardial Transplantation of Autologous Cardiac Micrografts During Coronary Artery Bypass Surgery.

Annu Nummi, Severi Mulari, Juhani A Stewart, Sari Kivistö, Kari Teittinen, Tuomo Nieminen, Milla Lampinen, Tommi Pätilä, Harri Sintonen, Tatu Juvonen and 6 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05632432 (Autologous Atrial Appendage Micrografts Transplanted During Coronary Artery Bypass Surgery), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05632432 narecruitingnot on this mapstarted 2024, after this paper: background citation

Autologous Atrial Appendage Micrografts Transplanted During Coronary Artery Bypass Surgery: the AAMS2 Randomized, Double-blinded, and Placebo-controlled Trial

TypeinterventionalSponsorHospital District of Helsinki and UusimaaRan2024 to 2026Enrolled50ConditionsIschemic Heart Disease, Ischemic Cardiomyopathy, Heart Failure, Systolic, Heart Failure NYHA Class IIIArmsEpicardial AAMs-patch transplantation, RNA-stabilized whole blood sampling, Plasma sampling, Transthoracic echocardiography, Late-gadolinium enhancement cardiac magnetic resonance imaging (LGE-CMRI)
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Cell sheet transplantation for ischemic heart disease: a systematic review.Indian journal of thoracic and cardiovascular surgery · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Annu NummiHeart and Lung Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Severi MulariHeart and Lung Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Juhani A StewartHeart and Lung Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Sari KivistöDepartment of Radiology, Helsinki University Hospital (HUS) Medical Imaging Center and Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Kari TeittinenHeart and Lung Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Tuomo NieminenDepartment of Internal Medicine, Päijät-Häme Central Hospital, Lahti, Finland.
Milla LampinenDepartment of Pharmacology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Tommi PätiläPediatric Cardiac Surgery, Children's Hospital, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Harri SintonenDepartment of Public Health, University of Helsinki, Helsinki, Finland.
Tatu JuvonenHeart and Lung Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Markku KupariHeart and Lung Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Raili SuojarantaDepartment of Anesthesiology and Intensive Care, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Esko KankuriDepartment of Pharmacology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Ari HarjulaHeart and Lung Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Antti VentoHeart and Lung Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
AADC consortium
University of Helsinki · FIHelsinki University Hospital · FIPäijät-Hämeen Keskussairaala · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

atrial appendageautologous micrograftscell therapycoronary artery bypass surgeryepicardial cell deliveryischemic heart failure

Identifiers

PMID34595223
PMCPMC8476794
OpenAlexW3201414107

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.