Evidence map›Paper›PMID 34595107›Full record

ArticleFrontiers in oncology2021

CT Radiomics for the Preoperative Prediction of Ki67 Index in Gastrointestinal Stromal Tumors: A Multi-Center Study.

Yilei Zhao, Meibao Feng, Minhong Wang, Liang Zhang, Meirong Li, Chencui Huang

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Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yilei ZhaoFirst Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Meibao FengFirst Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Minhong WangFirst Affiliated Hospital of Wannan Medical College, Wuhu, China.
Liang ZhangZhejiang Cancer Hospital, University of Chinese Academy of Sciences, Hangzhou, China.
Meirong LiFirst Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Chencui HuangBeijing Deepwise & League of PHD Technology Co., Ltd, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study established and verified a radiomics model for the preoperative prediction of the Ki67 index of gastrointestinal stromal tumors (GISTs). MATERIALS AND

methodsA total of 344 patients with GISTs from three hospitals were divided into a training set and an external validation set. The tumor region of interest was delineated based on enhanced computed-tomography (CT) images to extract radiomic features. The Boruta algorithm was used for dimensionality reduction of the features, and the random forest algorithm was used to construct the model for radiomics prediction of the Ki67 index. The receiver operating characteristic (ROC) curve was used to evaluate the model's performance and generalization ability.

resultsAfter dimensionality reduction, a feature subset having 21 radiomics features was generated. The generated radiomics model had an the area under curve (AUC) value of 0.835 (95% confidence interval(CI): 0.761-0.908) in the training set and 0.784 (95% CI: 0.691-0.874) in the external validation cohort.

conclusionThe radiomics model of this study had the potential to predict the Ki67 index of GISTs preoperatively.

Indexed as

computed-tomography (CT)gastrointestinal stromal tumors (GIST)ki67prognosticradiomics

Identifiers

PMID34595107
PMCPMC8476965

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