Evidence map›Paper›PMID 34594618›Full record

ArticleChina CDC weekly2020

Detection and Initial Response to a Type 2 Vaccine-Derived Poliovirus - Sichuan Province, China, 2019.

Jiushun Zhou, Ning Wen, Yong Zhang, Qi Qi, Chunxiang Fan, Dongmei Yan, Xiaoping Zhu, Lixin Hao, Shuangli Zhu, Yu Liu and 19 more

Abstract read
PubMed Full text at PMC
In one paragraph

Article in China CDC weekly, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Jiushun ZhouSichuan Provincial Center for Disease Control and Prevention, Chengdu, Sichuan, China.
Ning WenNational Immunization Program, Chinese Center for Disease Control and Prevention, Beijing, China.
Yong ZhangNational Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Qi QiSichuan Provincial Center for Disease Control and Prevention, Chengdu, Sichuan, China.
Chunxiang FanNational Immunization Program, Chinese Center for Disease Control and Prevention, Beijing, China.
Dongmei YanNational Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Xiaoping ZhuSichuan Provincial Center for Disease Control and Prevention, Chengdu, Sichuan, China.
Lixin HaoNational Immunization Program, Chinese Center for Disease Control and Prevention, Beijing, China.
Shuangli ZhuNational Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Yu LiuSichuan Provincial Center for Disease Control and Prevention, Chengdu, Sichuan, China.
Xiaozhen MaSichuan Provincial Center for Disease Control and Prevention, Chengdu, Sichuan, China.
Chao MaNational Immunization Program, Chinese Center for Disease Control and Prevention, Beijing, China.
Lei NanLiangshan Yi Autonomous Prefectural Center for Disease Control and Prevention, Xichang, Sichuan, China.
Yong ChenLeibo county Center for Disease Control and Prevention, Leibo, Liangshan, Sichuan, China.
Qianli MaSichuan Provincial Center for Disease Control and Prevention, Chengdu, Sichuan, China.
Cheng WangSichuan Provincial Center for Disease Control and Prevention, Chengdu, Sichuan, China.
Kun DengLiangshan Yi Autonomous Prefectural Center for Disease Control and Prevention, Xichang, Sichuan, China.
Lei CaoNational Immunization Program, Chinese Center for Disease Control and Prevention, Beijing, China.
Ge ShaoChinese Field Epidemiology Training Program.
Xianxiang DingChinese Field Epidemiology Training Program.
Hong YangNational Immunization Program, Chinese Center for Disease Control and Prevention, Beijing, China.
Zhijie AnNational Immunization Program, Chinese Center for Disease Control and Prevention, Beijing, China.
Lance E RodewaldChinese Center for Disease Control and Prevention, Beijing, China.
Aiqiang XuShandong Provincial Center for Disease Control and Prevention, Jinan, Shandong, China.
Huaqing WangNational Immunization Program, Chinese Center for Disease Control and Prevention, Beijing, China.
Zijian FengChinese Center for Disease Control and Prevention, Beijing, China.
Zundong YinNational Immunization Program, Chinese Center for Disease Control and Prevention, Beijing, China.
Xianping WuSichuan Provincial Center for Disease Control and Prevention, Chengdu, Sichuan, China.
Wenbo XuNational Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

WHAT IS ALREADY KNOWN ABOUT THIS TOPIC?: After the type 2 strain of the live, attenuated poliovirus vaccine was withdrawn globally in 2016, any identification of a type 2 poliovirus is a Public Health Emergency of International Concern. A vaccine-derived type 2 poliovirus (VDPV2) was identified in Sichuan, prompting an urgent, comprehensive investigation and response. WHAT IS ADDED BY THIS REPORT?: Type 2 monovalent, live, attenuated oral poliovirus vaccine (mOPV2) is being used to respond to the numerous VDPV2 outbreaks seen around the world. In contrast, the response in Sichuan used Sabin strain inactivated poliovirus (sIPV) to stop circulation of the VDPV2. In the 6 months following the vaccination response, there have been no VDPV2s detected in Sichuan, despite extensive search. WHAT ARE THE IMPLICATIONS FOR PUBLIC HEALTH PRACTICES?: Further search for the VDPV2 must continue in order to determine whether transmission has been stopped. The ongoing investigation and response to the Sichuan VDPV2 is providing evidence to the Global Polio Eradication Initiative on managing VDPV2 outbreaks.

Identifiers

PMID34594618
PMCPMC8393164

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.