Evidence map›Paper›PMID 34594556›Full record

ArticleClinical case reports2021

Use of Cerebrolysin in combination with high-dose aspirin antithrombotic treatment of ischemic stroke: A case report.

Alexander Borisevich, Konstantin Veremeyuk

Open access · goldAbstract readCase Reports
In one paragraph

Article in Clinical case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Alexander BorisevichBrest City Emergency Hospital Brest Belarus.ORCID https://orcid.org/0000-0002-1711-1458
Konstantin VeremeyukBrest City Emergency Hospital Brest Belarus.
Brest State Technical University · BY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This clinical case is an example of a potential synergistic neuroprotective interaction of Cerebrolysin and high doses of aspirin. The case describes the significant recovery of neurological deficits in a patient with moderate ischemic stroke (NIHSS 12 points) caused by right posterior cerebral artery thrombosis (RPCAT) after treatment with Cerebrolysin in combination with high dose of aspirin. Within 7 days after the initiation of the treatment regimen, the NIHSS score improved to 3 points and a control MRI that was performed on the 10th day after stroke, showed a significant decrease of the ischemic area and cerebral edema zone. It further might have an evidence that the combination of Cerebrolysin with high-dose aspirin is safe and might have a synergistic effect in the treatment of ischemic stroke.

Indexed as

aspirincerebrolysinischemic strokeposterior cerebral artery thrombosis

Identifiers

PMID34594556
PMCPMC8462435
OpenAlexW3175039016

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.