ReviewOxidative medicine and cellular longevity2021
Methods to Analyse Time-to-Event Data: The Kaplan-Meier Survival Curve.
Review in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.
- Endovascular versus open surgery repair of intact abdominal aortic aneurysm: systematic review of randomized controlled trials and critical appraisal of meta-analyses.Systematic reviews · 2026Pooled it
- Itch Relief and Quality-of-Life Improvement with Abrocitinib and Dupilumab in Patients with Moderate-to-Severe Atopic Dermatitis: A Post Hoc Analysis of JADE COMPARE and JADE DARE.American journal of clinical dermatology · 2026Trial
- Long-term thyroid outcomes and survival in hyperthyroid cats treated with radioiodine: association with overt and subclinical hypothyroidism and levothyroxine treatment.Journal of veterinary internal medicine · 2026Article
- Predictors of time to diabetic retinopathy in patients with type 2 diabetes mellitus: a survival analysis study.BMC ophthalmology · 2026Article
- Contrastive Machine Learning to Quantify Hypertensive Multiorgan Damage and Identify New Disease Phenotypes: A Multinational Multimodal Study.Circulation · 2026Article
- Decoding the functional landscape of long non-coding RNAs in hepatocellular carcinoma: molecular mechanisms, clinical implications, and therapeutic prospects.Journal of the Egyptian National Cancer Institute · 2026Review
- Digital personalized trials of a multicomponent behavioral change intervention for increasing habitual low-intensity physical activity in middle-aged and older healthcare workers: results of a feasibility study.Pilot and feasibility studies · 2026Article
- Later-generation epigenetic aging clocks outperform first-generation models in predicting survival in TCGA breast cancer.Clinical epigenetics · 2026Article
- The refinement of repeated exact time-to-event modeling: methodological refinements and implementation in NONMEMFrontiers in pharmacology · 2026Article
- Incident Falls Across Concordant and Discordant Profiles of Concerns About Falling and Functional Mobility in Older Adults: A Prospective Cohort Study.Clinical interventions in aging · 2026Article
- Article
- Survival analysis of time to reimbursement of novel medicines in five Eurasian countries.Global health research and policy · 2025Article
- The Fragile First Year: GPS Tracking Identifies Post-Release Survival Risks in Migratory Geese.Ecology and evolution · 2025Article
- Survival analysis of Kasturi tobacco plants in Jember district using the stratified cox and extended cox models.MethodsX · 2025Article
- Comprehensive analysis of FAM83B in pan-cancer and preliminary exploration in esophageal squamous cell carcinoma.Journal of molecular histology · 2025Article
- Remdesivir associated with reduced mortality in hospitalized COVID-19 patients: treatment effectiveness using real-world data and natural language processing.BMC infectious diseases · 2025Article
- FADS1, a lipid metabolism-related diagnostic biomarker in KIRC.Discover oncology · 2025Article
- Article
- A multisite study to develop and validate first trimester, circulating microparticle biomarkers for tiered risk stratification of spontaneous preterm birth in nulliparas.American journal of obstetrics and gynecology · 2025Article
- Association of pre- and post-diagnosis dietary total antioxidant capacity (TAC) and composite dietary antioxidant index (CDAI) with overall survival in patients with ovarian cancer: a prospective cohort study.Journal of translational medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Studies performed in the field of oxidative medicine and cellular longevity frequently focus on the association between biomarkers of cellular and molecular mechanisms of oxidative stress as well as of aging, immune function, and vascular biology with specific time to event data, such as mortality and organ failure. Indeed, time-to-event analysis is one of the most important methodologies used in clinical and epidemiological research to address etiological and prognostic hypotheses. Survival data require adequate methods of analyses. Among these, the Kaplan-Meier analysis is the most used one in both observational and interventional studies. In this paper, we describe the mathematical background of this technique and the concept of censoring (right censoring, interval censoring, and left censoring) and report some examples demonstrating how to construct a Kaplan-Meier survival curve and how to apply this method to provide an answer to specific research questions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.