Evidence map›Paper›PMID 34594421›Full record

ArticleOncology letters2021

Identification of soluble tissue-derived biomarkers from human thyroid tissue explants maintained on a microfluidic device.

Andrew Riley, Heidi Jones, James England, Dmitriy Kuvshinov, Victoria Green, John Greenman

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Andrew RileyFaculty of Health Sciences, University of Hull, Hull HU6 7RX, UK.
Heidi JonesDepartment of ENT, Hull University Teaching Hospitals NHS Trust, Castle Hill Hospital, Hull HU16 5JQ, UK.
James EnglandDepartment of ENT, Hull University Teaching Hospitals NHS Trust, Castle Hill Hospital, Hull HU16 5JQ, UK.
Dmitriy KuvshinovFaculty of Engineering, University of Hull, Cottingham Road, Hull HU6 7RX, UK.
Victoria GreenFaculty of Health Sciences, University of Hull, Hull HU6 7RX, UK.
John GreenmanFaculty of Health Sciences, University of Hull, Hull HU6 7RX, UK.
University of Hull · GBCastle Hill Hospital · GB

Funding

National Centre for the Replacement, Refinement and Reduction of Animals in Research G1100600/1
6 · The paper itself

Abstract

Although a large cohort of potential biomarkers for thyroid cancer aggressiveness have been tested in various formats in recent years, to the best of our knowledge, thyroglobulin and calcitonin remain the only two established biomarkers associated with thyroid cancer management. Our group has recently validated a novel means of maintaining live, human

Indexed as

biomarkermicrofluidicsserpin F1thyroidthyroid cancer

Identifiers

PMID34594421
PMCPMC8456457
OpenAlexW3199127590

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.