Evidence map›Paper›PMID 34594389›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2021

Saposhnikoviae Radix Enhanced the Angiogenic and Anti-Inflammatory Effects of Huangqi Chifeng Tang in a Rat Model of Cerebral Infarction.

Qiu-Yue Wang, Na Zhang, Shu-Yu Liu, Xi-Hong Jiang, Shu-Min Liu

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Qiu-Yue WangInstitute of Traditional Chinese Medicine, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
Na ZhangDrug Safety Evaluation Centre, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
Shu-Yu LiuInstitute of Traditional Chinese Medicine, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
Xi-Hong JiangInstitute of Traditional Chinese Medicine, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
Shu-Min LiuInstitute of Traditional Chinese Medicine, Heilongjiang University of Chinese Medicine, Harbin 150040, China.ORCID https://orcid.org/0000-0002-4812-3494
Heilongjiang University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Huangqi Chifeng Tang (HQCFT), a traditional Chinese formula of three herbs, has been used to treat cerebral infarction (CI). Saposhnikoviae Radix (SR) was designed as a guiding drug for HQCFT to improve its angiogenic and anti-inflammatory effects. In this study, TTC staining was used to detect the area of CI. H&E staining was used to detect the histopathologic changes in the cerebral tissue. Western blotting was performed to detect the protein expression of NLRP3, caspase 1, IL-1

Identifiers

PMID34594389
PMCPMC8478555
OpenAlexW3201048902

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.