Evidence map›Paper›PMID 34594124›Full record

ArticleClinical, cosmetic and investigational dermatology2021

The Picosecond Laser Effects on Tattoo Removal and Metabolic Pathways.

Yan Qu, Xien Feng, Jin'ning Liang, Junru Liu, Dong Gao

Open access · goldAbstract read
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Intravital Visualization of Tattoo Particles After Picosecond Laser Treatment.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2025
    Observational
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yan QuDepartment of Dermatology, The Affiliated Hospital of Weifang Medical University, Weifang, Shandong, 261031, People's Republic of China.
Xien FengDepartment of Dermatology, Yantai Yuhuangding Hospital, Yantai, 264003, Shandong, People's Republic of China.
Jin'ning LiangDepartment of Dermatology, Yantai Yuhuangding Hospital, Yantai, 264003, Shandong, People's Republic of China.
Junru LiuDepartment of Dermatology, Yantai Yuhuangding Hospital Laishan Branch, Yantai, 264003, Shandong, People's Republic of China.
Dong GaoDepartment of Dermatology, Yantai Yuhuangding Hospital, Yantai, 264003, Shandong, People's Republic of China.
Yuhuangding Hospital · CNWeifang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe aimed to investigate picosecond laser effects regarding rat tattoo removals. We systematically detected the metabolic pathways considering tattoo pigment particles in rat models. MATERIALS AND

methodsWe employed fluorescein to mark the tattoo dye and utilized a pattern needle to prepare tattoo on rat so as to establish the tattoo removal effects of picosecond laser methods employing animal models. We applied a picosecond laser to process the tattoo and observed the effects along with metabolic pathways for tattoo removal via pathology and imaging approaches.

resultsBased on the results of characterization, pathology and fluorescence, we discovered that the picosecond laser could effectively remove the pigment particles on rat skin, part of which would be metabolized out of the body through the circulatory system. After picosecond laser treatment, the fluorescence intensity of the rat skin engraved part was gradually weakened. At 8 h after the treatment, the metabolic organs had weak fluorescence, and there was no fluorescence in the metabolic organs at 12 h and 24 h after the treatment.

conclusionThe picosecond laser had perfect tattoo removal effects, which could be utilized as a reference for clinical tattoo removal.

Indexed as

dyepattern engravingpicosecond lasertattoo

Identifiers

PMID34594124
PMCPMC8478112
OpenAlexW3201547181

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.