Evidence map›Paper›PMID 34594098›Full record

ArticleEvolutionary bioinformatics online2021

Biomarkers of Blood from Patients with Atherosclerosis Based on Bioinformatics Analysis.

Yongjiang Qian, Lili Zhang, Zhen Sun, Guangyao Zang, Yalan Li, Zhongqun Wang, Lihua Li

Open access · goldAbstract read
In one paragraph

Article in Evolutionary bioinformatics online, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yongjiang QianDepartment of Cardiology, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
Lili ZhangDepartment of Cardiology, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
Zhen SunDepartment of Cardiology, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
Guangyao ZangDepartment of Cardiology, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
Yalan LiDepartment of Cardiology, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
Zhongqun WangDepartment of Cardiology, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
Lihua LiDepartment of Pathology, Affiliated Hospital of Jiangsu University, Zhenjiang, China.ORCID https://orcid.org/0000-0002-2089-8140
Jiangsu University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis is a multifaceted disease characterized by the formation and accumulation of plaques that attach to arteries and cause cardiovascular disease and vascular embolism. A range of diagnostic techniques, including selective coronary angiography, stress tests, computerized tomography, and nuclear scans, assess cardiovascular disease risk and treatment targets. However, there is currently no simple blood biochemical index or biological target for the diagnosis of atherosclerosis. Therefore, it is of interest to find a biochemical blood marker for atherosclerosis. Three datasets from the Gene Expression Omnibus (GEO) database were analyzed to obtain differentially expressed genes (DEG) and the results were integrated using the Robustrankaggreg algorithm. The genes considered more critical by the Robustrankaggreg algorithm were put into their own data set and the data set system with cell classification information for verification. Twenty-one possible genes were screened out. Interestingly, we found a good correlation between

Indexed as

atherosclerosisbioinformaticsbiomarkerBlood

Identifiers

PMID34594098
PMCPMC8477683
OpenAlexW3162359537

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.