Evidence map›Paper›PMID 34593921›Full record

ArticleScientific reports2021

Effectiveness of human-origin Lactobacillus plantarum PL-02 in improving muscle mass, exercise performance and anti-fatigue.

Mon-Chien Lee, Yi-Ju Hsu, Hsieh-Hsun Ho, Yi-Wei Kuo, Wen-Yang Lin, Shin-Yu Tsai, Wei-Ling Chen, Che-Li Lin, Chi-Chang Huang

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Effects ofFrontiers in nutrition · 2026
    Pooled it
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  5. Efficacy ofNutrients · 2024
    Trial
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  7. Article
  8. Review
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  12. Article
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  14. Foods (Basel, Switzerland) · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Mon-Chien LeeGraduate Institute of Sports Science, National Taiwan Sport University, Taoyuan City, 333325, Taiwan.
Yi-Ju HsuGraduate Institute of Sports Science, National Taiwan Sport University, Taoyuan City, 333325, Taiwan.
Hsieh-Hsun HoResearch and Development Department, Bioflag Biotech Co, Ltd, Tainan, Taiwan.
Yi-Wei KuoResearch and Development Department, Bioflag Biotech Co, Ltd, Tainan, Taiwan.
Wen-Yang LinResearch and Development Department, Bioflag Biotech Co, Ltd, Tainan, Taiwan.
Shin-Yu TsaiResearch and Development Department, Bioflag Biotech Co, Ltd, Tainan, Taiwan.
Wei-Ling ChenDepartment of Sports Training Science-Athletics, National Taiwan Sport University, Taoyuan City, 333325, Taiwan.
Che-Li LinDepartment of Orthopedics, School of Medicine, College of Medicine, Taipei Medical University, Taipei City, 11031, Taiwan. 11010@s.tmu.edu.tw.
Chi-Chang HuangGraduate Institute of Sports Science, National Taiwan Sport University, Taoyuan City, 333325, Taiwan. john5523@ntsu.edu.tw.
National Taiwan Sport University · TWTaipei Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gut microbiota is very important for energy metabolism and regulation, which in turn affect the health and physiological functions of the host, and provide energy required for exercise. Supplementation with probiotics may be one of the ways to change the gut microbiota. In recent years, many studies have shown that probiotic supplementation can effectively improve sports performance. In this study, we screened Lactobacillus plantarum (PL-02), a probiotic of human-origin, from the intestines of 2008 Olympic women's 48 kg weightlifting gold medalist and explored the role of PL-02 in improved exercise endurance performance, reduced fatigue biochemical parameters, and changes in body composition. Male Institute of Cancer Research (ICR) mice were assigned to 0, 2.05 × 10

Indexed as

Exercise ToleranceLactiplantibacillus plantarumMuscle StrengthAdministration, OralAnimalsFemaleGastrointestinal MicrobiomeGlycogenHumansLiverMaleMiceMice, Inbred ICRMuscle, SkeletalPhysical Conditioning, AnimalProbioticsGlycogen

Identifiers

PMID34593921
PMCPMC8484333
OpenAlexW3203482499

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.