Evidence map›Paper›PMID 34593519›Full record

ArticleeNeuro

Frequency-Dependent Action of Neuromodulation.

Anna C Schneider, David Fox, Omar Itani, Jorge Golowasch, Dirk Bucher, Farzan Nadim

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Modulation by Neuropeptides with Overlapping Targets Results in Functional Overlap in Oscillatory Circuit Activation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Anna C SchneiderFederated Department of Biological Sciences, New Jersey Institute of Technology and Rutgers University, Newark, NJ 07102.ORCID 0000-0002-1270-836X
David FoxFederated Department of Biological Sciences, New Jersey Institute of Technology and Rutgers University, Newark, NJ 07102.
Omar ItaniFederated Department of Biological Sciences, New Jersey Institute of Technology and Rutgers University, Newark, NJ 07102.ORCID 0000-0002-4694-5734
Jorge GolowaschFederated Department of Biological Sciences, New Jersey Institute of Technology and Rutgers University, Newark, NJ 07102.ORCID 0000-0002-6183-3175
Dirk BucherFederated Department of Biological Sciences, New Jersey Institute of Technology and Rutgers University, Newark, NJ 07102.ORCID 0000-0003-4144-2895
Farzan NadimFederated Department of Biological Sciences, New Jersey Institute of Technology and Rutgers University, Newark, NJ 07102 farzan@njit.edu.ORCID 0000-0003-4144-9042
Rutgers, The State University of New Jersey · USNew Jersey Institute of Technology · US

Funding

REGULATION OF NEURONAL OSCILLATIONS BY SYNAPTIC DYNAMICSR01MH060605 · NIMH · NEW JERSEY INSTITUTE OF TECHNOLOGY · PI Dirk Martin Bucher, Farzan Nadim · 2001 to 2026
$6.6M
The role of axons in neural codingR01NS083319 · NINDS · UNIVERSITY OF FLORIDA · PI BUCHER, DIRK MARTIN, NADIM, FARZAN · 2013 to 2017
$1.7M
NIMH NIH HHS R01 MH060605NINDS NIH HHS R01 NS083319
6 · The paper itself

Abstract

In oscillatory circuits, some actions of neuromodulators depend on the oscillation frequency. However, the mechanisms are poorly understood. We explored this problem by characterizing neuromodulation of the lateral pyloric (LP) neuron of the crab stomatogastric ganglion (STG). Many peptide modulators, including proctolin, activate the same ionic current (

Indexed as

BrachyuraNeurotransmitter AgentsAction PotentialsAnimalsGangliaGanglia, InvertebrateNeuronsPylorusNeurotransmitter Agentscalciumcentral pattern generatormodelingneuromodulationstomatogastric

Identifiers

PMID34593519
PMCPMC8584230
OpenAlexW3201892820

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.