Evidence map›Paper›PMID 34593496›Full record

ArticleBMJ open2021

Global access to COVID-19 vaccines: a scoping review of factors that may influence equitable access for low and middle-income countries.

Elizabeth F Peacocke, Lieke Fleur Heupink, Katrine Frønsdal, Elin Hoffmann Dahl, Lumbwe Chola

Abstract readScoping Review
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Racial and ethnic disparities in COVID-19 vaccination: a systematic review and meta-analysis.Archives of public health = Archives belges de sante publique · 2025
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Observational
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Elizabeth F PeacockeGlobal Health, Division for Health Services, Norwegian Institute of Public Health, Oslo, Norway elizabeth.peacocke@fhi.no.ORCID 0000-0001-6930-9581
Lieke Fleur HeupinkGlobal Health, Division for Health Services, Norwegian Institute of Public Health, Oslo, Norway.
Katrine FrønsdalGlobal Health, Division for Health Services, Norwegian Institute of Public Health, Oslo, Norway.
Elin Hoffmann DahlDepartment of Medicine, Haukeland University Hospital, Bergen, Norway.
Lumbwe CholaGlobal Health, Division for Health Services, Norwegian Institute of Public Health, Oslo, Norway.ORCID 0000-0001-6488-2813

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo identify the factors contributing to equitable access to COVID-19 vaccines for low and middle-income countries (LMIC).

methodsWe conducted a scoping review following the guidelines for Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews and a five-stage framework for scoping studies. We performed systematic searches for published peer-reviewed literature in five databases: Medline, Embase, Web of Science, Global Index Medicus and COVID-19 Evidence Epistemonikos (August 2020, updated May 2021).

resultsSystematic selection according to predefined criteria resulted in the final inclusion of 45 peer-reviewed articles, with no limitations on study design or publication type. We derived four key factors that potentially influence equitable access to COVID-19 vaccines in LMICs: (1) collectively agreed global mechanisms or frameworks; (2) bilateral purchasing, contracting, and vaccine prices; (3) vaccine manufacturing that is supported by sharing know-how; and (4) countries' strength in implementing vaccination programmes.

conclusionsThis scoping review highlights the ongoing challenges for the international community in ensuring equitable access to COVID-19 vaccines for LMICs. The literature suggests that vaccine manufacturing can influence the supply of vaccines, as can the role of patent holders who can influence global governance through their role in the distribution of COVID-19 vaccines. Our findings indicate that including the principles of equitable access throughout vaccine research and development, procurement, scale-up and distribution processes can support equitable access for LMICs. Advances made with mRNA vaccines may have additional benefits in relation to expanding the manufacturing of other vaccine. Finally, the exploration and scale-up of such capacities of LMICs are likely to prove to be a valuable investment, even after the pandemic.

Indexed as

COVID-19VaccinesCOVID-19 VaccinesDeveloping CountriesHumansSARS-CoV-2COVID-19 VaccinesVaccinesCOVID-19health policypublic health

Identifiers

PMID34593496
PMCPMC8487019

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.