ArticleBMC geriatrics2021
Prevalence and determinants of frailty in older adult patients with chronic coronary syndrome: a cross-sectional study.
Article in BMC geriatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Association between frailty and depression in older adults with coronary heart disease: a systematic review and meta-analysis.Frontiers in public health · 2026Pooled it
- The Caprini score for venous thromboembolism risk assessment: A scoping review of applications, validation, and future directions.Journal of vascular surgery. Venous and lymphatic disorders · 2026Article
- Frailty Syndrome and Depressive Symptoms in Patients with Ischemic Heart Disease.Diagnostics (Basel, Switzerland) · 2026Article
- Sex-specific associations of physical frailty with cardiac structure and function: a cross-sectional study based on UK Biobank.BMC cardiovascular disorders · 2026Article
- Frailty identifies early and non-cardiac healthcare utilization after cardiovascular hospitalization.Frontiers in cardiovascular medicine · 2026Article
- Predictive Risk Models for Frailty Onset in Older Adults: A Scoping Review of Methodological Trends, Model Performance, and Clinical Translation Gap.Clinical interventions in aging · 2026Article
- Status of comprehensive geriatric assessment in hospital settings: a cross-sectional survey.Frontiers in medicine · 2025Article
- Long-term health related quality of life in adult extracorporeal membrane oxygenation survivors: a single-centre, cross-sectional study.BMC public health · 2024Article
- Fried Frailty Phenotype in Elderly Patients with Chronic Coronary Syndrome: Prevalence, Associated Factors, and Impact on Hospitalization.Journal of multidisciplinary healthcare · 2024Article
- Factors associated with frailty among older individuals with chronic diseases: A multicenter study.SAGE open medicine · 2024Article
- Development and internal and external validation of a nomogram model for frailty risk among hospitalised older people using comprehensive geriatric assessment data.BMC geriatrics · 2023Article
- Implication of different frailty criteria in older people with atrial fibrillation: a prospective cohort study.BMC geriatrics · 2023Article
- Developing a Parsimonious Frailty Index for Older, Multimorbid Adults With Heart Failure Using Machine Learning.The American journal of cardiology · 2023Article
- Chronic Coronary Syndrome in Frail Old Population.Life (Basel, Switzerland) · 2022Review
- A relationship among the blood serum levels of interleukin-6, albumin, and 25-hydroxyvitamin D and frailty in elderly patients with chronic coronary syndrome.Aging medicine (Milton (N.S.W)) · 2022Article
- Frailty Syndrome in Older Adults with Cardiovascular Diseases-What Do We Know and What Requires Further Research?International journal of environmental research and public health · 2022Review
- Analysis of the blood bacterial composition of patients with acute coronary syndrome and chronic coronary syndrome.Frontiers in cellular and infection microbiology · 2022Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFrailty is an expression of vulnerability and decline of physical, mental, and social activities, more commonly found in older adults. It is also closely related to the occurrence and poor prognosis of coronary artery disease (CAD). Little investigation has been conducted on the prevalence and determinants of frailty in older adult patients with chronic coronary syndrome (CCS).
methodsA cross-sectional study was conducted, simple random sampling was used in this study. 218 older adults (age ≥ 60 years) with CCS with an inpatient admission number ending in 6 were randomly selected who hospitalized in Department of Geriatric Cardiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, China, between January and December 2018. For measurement and assessment, we used the 5-item FRAIL scale (fatigue, resistance, ambulation, illnesses, and loss of weight), demographic characteristics, Barthel Index(BI), Mini-Mental State Examination (MMSE), Geriatric Depression Scale (GDS-15), Mini Nutrition Assessment Shor-Form (MNA-SF), Morse Fall Scale (MFS), Caprini risk assessment, polypharmacy, and Numerical Rating Scale (NRS). Multivariate logistic regression analysis was used to confirme determinants.
resultsThe FRAIL scale showed 30.3% of the subjects suffered from frailty. Determinants were aging (OR1.12; 95% CI 1.04 ~ 1.62), out-of-pocket (OR18.93; 95% CI 1.11 ~ 324.07), hearing dysfunction (OR9.43; 95% CI 1.61 ~ 55.21), MNA-SF score (OR0.71; CI 0.57 ~ 0.89), GDS-15 score (OR1.35; 95% CI 1.11 ~ 1.64), and Caprini score (OR1.34; 95% CI 1.06 ~ 1.70).
conclusionsThe FRAIL scale confirmed that the prevalence of frailty in patients with CCS was slightly lower than CAD. Aging, malnutrition, hearing dysfunction, depression, and VTE risk were significantly associated with frail for older adult patients with CCS. A comprehensive assessment of high-risk patients can help identify determinants for frailty progression. In the context of CCS, efforts to identify frailty are needed, as are interventions to limit or reverse frailty status in older CCS patients.
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