Evidence map›Paper›PMID 34592946›Full record

ArticleBMC infectious diseases2021

Association between tuberculosis in men and social network structure in Kampala, Uganda.

Paige B Miller, Sarah Zalwango, Ronald Galiwango, Robert Kakaire, Juliet Sekandi, Lauren Steinbaum, John M Drake, Christopher C Whalen, Noah Kiwanuka

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

  1. Pooled it
  2. Community-Wide Universal HIV Test and Treat Intervention Reduces Tuberculosis Transmission in Rural Uganda: A Cluster-Randomized Trial.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Trial
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  12. Factors associated with unfavourable treatment outcomes among tuberculosis patients at health facilities of Maseru, Lesotho.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2024
    Article
  13. Who Transmits Tuberculosis to Whom: A Cross-Sectional Analysis of a Cohort Study in Lima, Peru.American journal of respiratory and critical care medicine · 2024
    Article
  14. Article
  15. Incidence of tuberculous infection in a TB-endemic city.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2024
    Article
  16. Open forum infectious diseases · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Paige B MillerOdum School of Ecology, University of Georgia, Athens, GA, 30602, USA.
Sarah ZalwangoKampala Capital City Authority, Kampala, Uganda.
Ronald GaliwangoMakerere University School of Public Health, Kampala, Uganda.
Robert KakaireGlobal Health Institute, College of Public Health, University of Georgia, 100 Foster Drive, Athens, GA, 30602, USA.
Juliet SekandiGlobal Health Institute, College of Public Health, University of Georgia, 100 Foster Drive, Athens, GA, 30602, USA.
Lauren SteinbaumDepartment of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens, GA, 30602, USA.
John M DrakeOdum School of Ecology, University of Georgia, Athens, GA, 30602, USA.
Christopher C WhalenGlobal Health Institute, College of Public Health, University of Georgia, 100 Foster Drive, Athens, GA, 30602, USA. ccwhalen@uga.edu.ORCID http://orcid.org/0000-0002-8081-0665
Noah KiwanukaMakerere University School of Public Health, Kampala, Uganda.
University of Georgia · USMakerere University · UGKampala Capital City Authority · UG

Funding

Community Transmission of Tuberculosis Urban AfricaR01AI093856 · NIAID · UNIVERSITY OF GEORGIA · PI WHALEN, CHRISTOPHER C. · 2012 to 2021
$5.7M
Tuberculosis Prevention Research Unit /TBRU/-266095383N01AI095383 · NIAID · CASE WESTERN RESERVE UNIVERSITY · 2000 to 2005
$5.6M
National Institutes of Health (US) RO1-AI093856National Science Foundation DGE-1545433NIAID NIH HHS N01 AI095383NIAID NIH HHS R01 AI093856NIH HHS D43-TW01004NIH HHS NO1-AI95383
6 · The paper itself

Abstract

backgroundGlobally, tuberculosis disease (TB) is more common among males than females. Recent research proposes that differences in social mixing by sex could alter infection patterns in TB. We examine evidence for two mechanisms by which social-mixing could increase men's contact rates with TB cases. First, men could be positioned in social networks such that they contact more people or social groups. Second, preferential mixing by sex could prime men to have more exposure to TB cases.

methodsWe compared the networks of male and female TB cases and healthy matched controls living in Kampala, Uganda. Specifically, we estimated their positions in social networks (network distance to TB cases, degree, betweenness, and closeness) and assortativity patterns (mixing with adult men, women, and children inside and outside the household).

resultsThe observed network consisted of 11,840 individuals. There were few differences in estimates of node position by sex. We found distinct mixing patterns by sex and TB disease status including that TB cases have proportionally more adult male contacts and fewer contacts with children.

conclusionsThis analysis used a network approach to study how social mixing patterns are associated with TB disease. Understanding these mechanisms may have implications for designing targeted intervention strategies in high-burden populations.

Indexed as

TuberculosisAdultChildFamily CharacteristicsFemaleHumansMaleSocial NetworkingUgandaContact patternsMale-biasSocial networkTuberculosis

Identifiers

PMID34592946
PMCPMC8482622
OpenAlexW3203647108

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.