Evidence map›Paper›PMID 34592885›Full record

ArticleRenal failure2021

Platelet-to-albumin ratio: a risk factor associated with technique failure and mortality in peritoneal dialysis patients.

Yuqi Yang, Jing Yuan, Lu Liu, Shuwen Qie, Li Yang, Zha Yan

Abstract read
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Article in Renal failure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

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18citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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18 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Yuqi YangDepartment of Nephrology, Guizhou Provincial People's Hospital, Guiyang, China.
Jing YuanDepartment of Nephrology, Guizhou Provincial People's Hospital, Guiyang, China.
Lu LiuDepartment of Nephrology, Guizhou Provincial People's Hospital, Guiyang, China.
Shuwen QieDepartment of Nephrology, Guizhou Provincial People's Hospital, Guiyang, China.
Li YangDepartment of Nephrology, Guizhou Provincial People's Hospital, Guiyang, China.
Zha YanDepartment of Nephrology, Guizhou Provincial People's Hospital, Guiyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeritoneal dialysis (PD) patients have a high incidence of poor clinical outcomes, which is related to the inflammatory and nutritional status of this population. Platelet-to-albumin ratio (PAR), recently identified as a useful biomarker to monitor inflammation and nutrition, can predict a poor prognosis in various diseases. The aim of this study was to investigate the association between PAR and technique failure and mortality in PD patients.

methodsThis single-center retrospective study enrolled 405 PD patients from 1 January 2011 to 31 December 2019 and collected complete demographic characteristics, clinical laboratory baseline data. The outcomes were technique failure and mortality. The associations between PAR and technique failure, death were analyzed by Cox proportional hazard models and competing risk regression models with kidney transplantation as a competing event. The areas under the curve (AUC) of receiver-operating characteristic analysis were used to determine the predictive values of PAR for technique failure and mortality.

resultsDuring a median follow-up period of 24.0 (range, 4.0-91.0) months, 139 (34.3%) PD patients experienced technique failure, 61 (15.1%) PD patients died. The patients with higher PAR levels had increased risk of technique failure and mortality. After adjustment for confounding factors, we found that high PAR levels were risk factor for both technique failure (subdistribution hazard ratio [

conclusionsPAR was a risk factor associated with technique failure and mortality in PD patients.

Indexed as

AdultArea Under CurveBiomarkersBlood PlateletsChinaFemaleHumansKidney TransplantationMaleMiddle AgedMultivariate AnalysisPeritoneal DialysisPredictive Value of TestsProportional Hazards ModelsRetrospective StudiesRisk FactorsBiomarkersSerum Albuminmortalityperitoneal dialysisPlatelet-to-albumin ratiotechnique failure

Identifiers

PMID34592885
PMCPMC8491659

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.