Evidence map›Paper›PMID 34592882›Full record

ArticleBioengineered2021

Overexpressing long non-coding RNA OIP5-AS1 ameliorates sepsis-induced lung injury in a rat model via regulating the miR-128-3p/Sirtuin-1 pathway.

Haibo Xie, Hanfei Chai, Xiaohong Du, Rongna Cui, Yinan Dong

Open access · goldAbstract readVideo-Audio Media
In one paragraph

Article in Bioengineered, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Haibo XieDepartment of Critical Care Medicine, Zhoushan Maternal and Child Health Hospital, Zhoushan, Zhejiang, China.
Hanfei ChaiDepartment of Critical Care Medicine, Zhoushan Maternal and Child Health Hospital, Zhoushan, Zhejiang, China.
Xiaohong DuDepartment of Critical Care Medicine, Zhoushan Maternal and Child Health Hospital, Zhoushan, Zhejiang, China.
Rongna CuiDepartment of Critical Care Medicine, Zhoushan Maternal and Child Health Hospital, Zhoushan, Zhejiang, China.
Yinan DongDepartment of Critical Care Medicine, Zhoushan Maternal and Child Health Hospital, Zhoushan, Zhejiang, China.
Zhoushan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sepsis, resulting from infections, is a systemic inflammatory response syndrome with a high fatality rate. The present study revolves around probing into the function and molecular mechanism of long non-coding RNA OIP5 antisense RNA 1 (lncRNA OIP5-AS1) in modulating acute lung injury (ALI) mediated by sepsis. Here, a sepsis model was constructed using cecal ligation and puncture (CLP) surgery

Indexed as

Signal TransductionAcute Lung InjuryAnimalsDisease Models, AnimalLungMaleMicroRNAsRatsRats, Sprague-DawleyRNA, Long NoncodingSepsisSirtuin 1MicroRNAsMIRN128 microRNA, ratRNA, Long NoncodingSirt1 protein, ratSirtuin 1lung injurymiR-128-3pOIP5-AS1SepsisSIRT1

Identifiers

PMID34592882
PMCPMC8809967
OpenAlexW3203909538

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.