Evidence map›Paper›PMID 34592704›Full record

ArticleDrug and alcohol dependence2021

Test-retest reliability and cross-cultural applicability of DSM-5 adopted diagnostic criteria for ketamine use disorders.

Nicole D Fitzgerald, Catherine W Striley, Joseph J Palamar, Jan Copeland, Steven Kurtz, Linda B Cottler

Open access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Characteristics of poisonings involving ketamine in the United States, 2019-2021.Journal of psychopharmacology (Oxford, England) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Nicole D FitzgeraldDepartment of Epidemiology, College of Public Health and Health Professions, College of Medicine, University of Florida, PO Box 100231, Gainesville, FL 32610, USA. Electronic address: nfitzgerald@ufl.edu.
Catherine W StrileyDepartment of Epidemiology, College of Public Health and Health Professions, College of Medicine, University of Florida, PO Box 100231, Gainesville, FL 32610, USA.
Joseph J PalamarDepartment of Population Health, New York University Grossman School of Medicine, 180 Madison Avenue, New York, NY 10016, USA.
Jan CopelandNational Drug and Alcohol Research Centre, University of New South Wales, NDW 2052, Australia.
Steven KurtzCenter for Applied Research on Substance Use and Health Disparities, Nova Southeastern University, Miami, FL 33138, USA.
Linda B CottlerDepartment of Epidemiology, College of Public Health and Health Professions, College of Medicine, University of Florida, PO Box 100231, Gainesville, FL 32610, USA.
University of Florida · USFlorida College · USNew York University · USNova Southeastern University · USUNSW Sydney · AU

Funding

National Drug Early Warning System (NDEWS) COVID-19 SupplementU01DA051126 · NIDA · UNIVERSITY OF FLORIDA · PI Linda B. Cottler, Joseph J Palamar · 2020 to 2026
$6.3M
UF Substance Abuse Training Center in Public HealthT32DA035167 · NIDA · UNIVERSITY OF FLORIDA · PI Linda B. Cottler · 2014 to 2026
$4.8M
Drug use among nightclub and dance festival attendees in New York CityR01DA044207 · NIDA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI PALAMAR, JOSEPH J · 2018 to 2021
$1.5M
NIDA NIH HHS R01 DA044207NIDA NIH HHS T32 DA035167NIDA NIH HHS U01 DA051126
6 · The paper itself

Abstract

backgroundDespite increasing prevalence of nonmedical ketamine use globally, data on ketamine use disorders, which are classified in the DSM-5 under criteria for phencyclidine, are limited. This study assessed the reliability and applicability of DSM-based diagnostic criteria for ketamine use disorder.

methodsParticipants who used ecstasy were recruited through the Tri-City Study of Club Drug Use, Abuse, and Dependence in St. Louis, Miami, and Sydney. Those who reported using ketamine (lifetime use >5 times) were included in these analyses (n = 205). Participants were interviewed using the computerized Substance Abuse Module for Club Drugs (CD-SAM) at baseline and 7 days later for the reliability of diagnoses and individual diagnostic criteria.

resultsOverall, 29.3% met DSM-5 adopted criteria for ketamine use disorder at Time 1. Moderate to excellent test-retest reliability was observed consistently across study sites for any ketamine use disorder (κ = 0.57, Y = 0.61) and severe ketamine use disorder (κ = 0.62, Y = 0.79). Continued use of ketamine despite knowledge of physical or psychological problems was the most frequently endorsed individual criterion (59.0%), followed by reported withdrawal (30.2%) and physically hazardous use (29.8%). All individual criteria had acceptable reliability estimates (κ ≥ 0.41).

conclusionsDiagnoses of ketamine use disorder can be reliably evaluated using this fully structured diagnostic instrument's questions and algorithm. Ketamine-related withdrawal among people who use ketamine should be re-evaluated. Considering that after-effects of this dissociative anesthetic can last for many hours, it is important to explore a different timeframe for possible withdrawal effects.

Indexed as

KetamineSubstance-Related DisordersCross-Cultural ComparisonDiagnostic and Statistical Manual of Mental DisordersHumansReproducibility of ResultsKetamineDSM-5EpidemiologyKetamineNosologyReliabilityTest-retest

Identifiers

PMID34592704
PMCPMC8678918
OpenAlexW3201149869

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.