Evidence map›Paper›PMID 34591960›Full record

ArticleNucleic acids research2022

Regeneration Roadmap: database resources for regenerative biology.

Wang Kang, Tong Jin, Tao Zhang, Shuai Ma, Haoteng Yan, Zunpeng Liu, Zhejun Ji, Yusheng Cai, Si Wang, Moshi Song and 7 more

Abstract read
In one paragraph

Article in Nucleic acids research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Biomarkers of aging.Science China. Life sciences · 2023
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. The landscape of aging.Science China. Life sciences · 2022
    Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Wang KangState Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
Tong JinChina National Center for Bioinformation, Beijing 100101, China.
Tao ZhangChina National Center for Bioinformation, Beijing 100101, China.
Shuai MaState Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
Haoteng YanAdvanced Innovation Center for Human Brain Protection, and National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital Capital Medical University, Beijing 100053, China.
Zunpeng LiuInstitute for Stem cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China.
Zhejun JiInstitute for Stem cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China.
Yusheng CaiState Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
Si WangAdvanced Innovation Center for Human Brain Protection, and National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital Capital Medical University, Beijing 100053, China.
Moshi SongState Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
Jie RenChina National Center for Bioinformation, Beijing 100101, China.
Baoyang HuInstitute for Stem cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China.
Qi ZhouInstitute for Stem cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China.
Weiqi ZhangChina National Center for Bioinformation, Beijing 100101, China.
Jing QuInstitute for Stem cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China.
Yiming BaoChina National Center for Bioinformation, Beijing 100101, China.
Guang-Hui LiuState Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.ORCID 0000-0001-9289-8177

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regeneration plays an instrumental role in biological development and damage repair by constructing and replacing cells, tissues, and organs. Since regenerative capacity declines with age, promoting regeneration is heralded as a potential strategy for delaying aging. On this premise, mechanisms that regulate regeneration have been extensively studied across species and in different tissues. However, an open and comprehensive database collecting and standardizing the abundant data generated in regeneration research, such as high-throughput sequencing data, remains to be developed. In this work, we constructed Regeneration Roadmap to systematically and comprehensively collect such information over 2.38 million data entries across 11 species and 36 tissues, including regeneration-related genes, bulk and single-cell transcriptomics, epigenomics, and pharmacogenomics data. In this database, users can explore regulatory and expression changes of regeneration-associated genes in different species and tissues. Regeneration Roadmap provides the research community with a long-awaited and valuable data resource featuring convenient computing and visualizing tools, which is publicly available at https://ngdc.cncb.ac.cn/regeneration/index.

Indexed as

Databases, FactualDatabases, GeneticAgingAnimalsEpigenomicsHumansRegenerationTranscriptome

Identifiers

PMID34591960
PMCPMC8728239

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.