Evidence map›Paper›PMID 34591780›Full record

ArticleJMIR public health and surveillance2021

Association of Substance Use With Behavioral Adherence to Centers for Disease Control and Prevention Guidelines for COVID-19 Mitigation: Cross-sectional Web-Based Survey.

Mollie A Monnig, Hayley Treloar Padovano, Alexander W Sokolovsky, Grace DeCost, Elizabeth R Aston, Carolina L Haass-Koffler, Claire Szapary, Patience Moyo, Jaqueline C Avila, Jennifer W Tidey and 2 more

Abstract read
In one paragraph

Article in JMIR public health and surveillance, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mollie A MonnigDepartment of Behavioral and Social Sciences, Brown University, Providence, RI, United States.ORCID 0000-0002-3166-2336
Hayley Treloar PadovanoDepartment of Behavioral and Social Sciences, Brown University, Providence, RI, United States.ORCID 0000-0001-5347-4291
Alexander W SokolovskyDepartment of Behavioral and Social Sciences, Brown University, Providence, RI, United States.ORCID 0000-0003-3545-5745
Grace DeCostCenter for Addiction and Disease Risk Exacerbation, Brown University, Providence, RI, United States.ORCID 0000-0001-8535-5254
Elizabeth R AstonDepartment of Behavioral and Social Sciences, Brown University, Providence, RI, United States.ORCID 0000-0001-6965-318X
Carolina L Haass-KofflerDepartment of Behavioral and Social Sciences, Brown University, Providence, RI, United States.ORCID 0000-0002-5634-5679
Claire SzaparyCenter for Addiction and Disease Risk Exacerbation, Brown University, Providence, RI, United States.ORCID 0000-0001-6723-2744
Patience MoyoCenter for Addiction and Disease Risk Exacerbation, Brown University, Providence, RI, United States.ORCID 0000-0003-1323-4554
Jaqueline C AvilaCenter for Addiction and Disease Risk Exacerbation, Brown University, Providence, RI, United States.ORCID 0000-0003-2019-6453
Jennifer W TideyDepartment of Behavioral and Social Sciences, Brown University, Providence, RI, United States.ORCID 0000-0002-8651-4947
Peter M MontiDepartment of Behavioral and Social Sciences, Brown University, Providence, RI, United States.ORCID 0000-0002-9185-4081
Jasjit S AhluwaliaDepartment of Behavioral and Social Sciences, Brown University, Providence, RI, United States.ORCID 0000-0003-1756-3646

Funding

Using wearables and EMA to examine the links between cannabis and depressionP20GM130414 · NIGMS · BROWN UNIVERSITY · PI Lauren Gioia Micalizzi · 2019 to 2026
$22.0M
A focus on alpha-1 blockade as a novel pharmacological treatment for alcohol use disorderR01AA027760 · NIAAA · BROWN UNIVERSITY · PI HAASS-KOFFLER, CAROLINA LUISA · 2019 to 2023
$2.6M
Lead optimization of novel CRFBP-CRFR2 complex modulators for alcohol use disorderR01AA026589 · NIAAA · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI SHEFFLER, DOUGLAS J · 2019 to 2021
$2.4M
Immune Activation and Neurodegeneration in HIV Infection and Heavy DrinkingK23AA024704 · NIAAA · BROWN UNIVERSITY · PI MONNIG, MOLLIE A · 2016 to 2021
$1.1M
Dual Use of ENDS and Combustible Cigarettes: Shared, Distinct, and Cross-Conditioned ProcessesK08DA048137 · NIDA · BROWN UNIVERSITY · PI SOKOLOVSKY, ALEXANDER WILLIAM · 2020 to 2024
$976k
Novel Approaches to Understanding How Alcohol Pathology Develops in AdolescentsK23AA024808 · NIAAA · BROWN UNIVERSITY · PI TRELOAR PADOVANO, HAYLEY · 2017 to 2021
$973k
Behavioral Economic Analysis of Demand for MarijuanaK01DA039311 · NIDA · BROWN UNIVERSITY · PI ASTON, ELIZABETH · 2015 to 2019
$902k
Mifepristone As A Pharmacological Intervention For Stress-Induced Alcohol DrinkingK01AA023867 · NIAAA · BROWN UNIVERSITY · PI HAASS-KOFFLER, CAROLINA LUISA · 2016 to 2020
$901k
Probenecid as pharmacotherapy for alcohol use disorderR21AA027614 · NIAAA · BROWN UNIVERSITY · PI HAASS-KOFFLER, CAROLINA LUISA · 2020 to 2021
$427k
NIAAA NIH HHS K01 AA023867NIAAA NIH HHS K23 AA024704NIAAA NIH HHS K23 AA024808NIAAA NIH HHS R01 AA026589NIAAA NIH HHS R01 AA027760NIAAA NIH HHS R21 AA027614NIDA NIH HHS K01 DA039311NIDA NIH HHS K08 DA048137NIGMS NIH HHS P20 GM130414
6 · The paper itself

Abstract

backgroundSubstance use is a risk factor for COVID-19 infection and adverse outcomes. However, reasons for elevated risk for COVID-19 in substance users are not well understood.

objectiveThe aim of this study was to evaluate whether alcohol or other drug use is associated with adherence to Centers for Disease Control and Prevention (CDC) guidelines for COVID-19 mitigation. Preregistered analyses tested the hypothesis that greater use of alcohol and other drugs would be associated with lower CDC guideline adherence. A secondary objective was to determine whether substance use was associated with the likelihood of COVID-19 testing or outcome.

methodsA cross-sectional web-based survey was administered to a convenience sample recruited through Amazon's Mechanical Turk platform from June 18 to July 19, 2020. Individuals aged 18 years or older and residing in Connecticut, Massachusetts, New Jersey, New York, or Rhode Island were eligible to participate. The exposure of interest was past 7-day use of alcohol, cigarettes, electronic cigarettes, cannabis, stimulants, and nonmedical opioids. The primary outcome was CDC guideline adherence measured using a scale developed from behaviors advised to reduce the spread of COVID-19. Secondary outcomes were likelihood of COVID-19 testing and a positive COVID-19 test result. All analyses accounted for the sociodemographic characteristics.

resultsThe sample consisted of 1084 individuals (mean age 40.9 [SD 13.4] years): 529 (48.8%) men, 543 (50.1%) women, 12 (1.1%) other gender identity, 742 (68.5%) White individuals, 267 (24.6%) Black individuals, and 276 (25.5%) Hispanic individuals. Daily opioid users reported lower CDC guideline adherence than nondaily users (B=-0.24, 95% CI -0.44 to -0.05) and nonusers (B=-0.57, 95% CI -0.76 to -0.38). Daily alcohol drinkers reported lower adherence than nondaily drinkers (B=-0.16, 95% CI -0.30 to -0.02). Nondaily alcohol drinkers reported higher adherence than nondrinkers (B=0.10, 95% CI 0.02-0.17). Daily opioid use was related to greater odds of COVID-19 testing, and daily stimulant use was related to greater odds of a positive COVID-19 test.

conclusionsIn a regionally-specific, racially, and ethnically diverse convenience sample, adults who engaged in daily alcohol or opioid use reported lower CDC guideline adherence for COVID-19 mitigation. Any opioid use was associated with greater odds of COVID-19 testing, and daily stimulant use was associated with greater odds of COVID-19 infection. Cigarettes, electronic cigarettes, cannabis, or stimulant use were not statistically associated with CDC guideline adherence, after accounting for sociodemographic covariates and other substance use variables. Findings support further investigation into whether COVID-19 testing and vaccination should be expanded among individuals with substance-related risk factors.

Indexed as

COVID-19Electronic Nicotine Delivery SystemsSubstance-Related DisordersAdultCenters for Disease Control and Prevention, U.S.COVID-19 TestingCross-Sectional StudiesFemaleGender IdentityHumansInternetMaleSARS-CoV-2United Statesaddictionalcohol drinkingalcohol useCOVID-19mental healthnicotinenovel coronavirusopioid usepandemicSARS-CoV-2smokingstimulant usesubstance abusesurvey

Identifiers

PMID34591780
PMCPMC8582757

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.