ArticleEmotion (Washington, D.C.)2022
Individual variation in white matter microstructure is related to better recovery from negative stimuli.
Article in Emotion (Washington, D.C.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 12 citations in OpenAlex.
- White Matter Regional Volumes in Relation to Menstrual Cycle Phase and Premenstrual Dysphoric Disorder.Biological psychiatry global open science · 2025Article
- The mediating effect of the amygdala-frontal circuit on the association between depressive symptoms and cognitive function in Alzheimer's disease.Translational psychiatry · 2024Article
- Altered intersubject functional variability of brain white-matter in major depressive disorder and its association with gene expression profiles.Human brain mapping · 2024Article
- Temporal dynamics of positive emotion regulation: insights from facial electromyography.Frontiers in human neuroscience · 2024Article
- Corticolimbic structural connectivity encapsulates real-world emotional reactivity and happiness.Social cognitive and affective neuroscience · 2023Article
- Structural connectome-based prediction of trait anxiety.Brain imaging and behavior · 2022Article
- Morphological similarity of amygdala-ventral prefrontal pathways represents trait anxiety in younger and older adults.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Differences in Emotion Expression, Suppression, and Cardiovascular Consequences Between Black and White Americans in the Midlife in the United States (MIDUS) Study.Psychosomatic medicineArticle
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Authors and funding
9 authors.
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Abstract
The uncinate fasciculus is a white matter tract that may facilitate emotion regulation by carrying connections from the prefrontal cortex to regions of the temporal lobe, including the amygdala. Depression and anxiety are associated with reduced uncinate fasciculus fractional anisotropy (FA)-a diffusion tensor imaging measure related to white matter integrity. In the current study, we tested whether FA in the uncinate fasciculus is associated with individual differences in emotional recovery measured with corrugator supercilii electromyography in response to negative, neutral, and positive images in 108 participants from the Midlife in the US (MIDUS; http://midus.wisc.edu) Refresher study. Corrugator activity is linearly associated with changes in affect, and differentiated negative, neutral, and positive emotional responses. Higher uncinate fasciculus FA was associated with lower corrugator activity 4-8 seconds after negative image offset, indicative of better recovery from negative provocation. In an exploratory analysis, we found a similar association for the inferior fronto-occipital, inferior longitudinal and superior longitudinal fasciculi. These results suggest that the microstructural features of the uncinate fasciculus, and these other association white matter fibers, may support emotion regulatory processes with greater white matter integrity facilitating healthier affective functioning. (PsycInfo Database Record (c) 2022 APA, all rights reserved).
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