Evidence map›Paper›PMID 34591309›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2022

Vascular Imaging in Small Animals Using Clinical Ultrasound Scanners.

Aung Moe Zaw, Richard Shangguan, Yuan Yao, YeJin Jeong, Billy Y S Yiu, Adrian J Y Chee, Alfred C H Yu, Evelyn K F Yim

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 77% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Aung Moe ZawRegenerative Nanomedicine Lab, Department of Chemical Engineering, University of Waterloo, Waterloo, ON, Canada.
Richard ShangguanSchlegel Research Institute for Aging, Department of Electrical & Computer Engineering, University of Waterloo, Waterloo, ON, Canada.
Yuan YaoRegenerative Nanomedicine Lab, Department of Chemical Engineering, University of Waterloo, Waterloo, ON, Canada.
YeJin JeongRegenerative Nanomedicine Lab, Department of Chemical Engineering, University of Waterloo, Waterloo, ON, Canada.
Billy Y S YiuSchlegel Research Institute for Aging, Department of Electrical & Computer Engineering, University of Waterloo, Waterloo, ON, Canada.
Adrian J Y CheeSchlegel Research Institute for Aging, Department of Electrical & Computer Engineering, University of Waterloo, Waterloo, ON, Canada.
Alfred C H YuSchlegel Research Institute for Aging, Department of Electrical & Computer Engineering, University of Waterloo, Waterloo, ON, Canada.
Evelyn K F YimRegenerative Nanomedicine Lab, Department of Chemical Engineering, University of Waterloo, Waterloo, ON, Canada. eyim@uwaterloo.ca.
University of Waterloo · CAResearch Institute for Aging · CA

Funding

Surface Modification Compliant Vascular GraftsR01HL130274 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI HINDS, MONICA T, YIM, EVELYN KING FAI · 2016 to 2019
$2.6M
NHLBI NIH HHS R01 HL130274
6 · The paper itself

Abstract

Conventional ultrasound with frequency (2-15 MHz) has been a global diagnostic and therapeutic tool in clinical medicine, and high-frequency ultrasound (>30 MHz) has been a powerful investigative device for preclinical studies such as cardiovascular research. In this chapter, we describe the use of conventional ultrasound with a 2.5-10 MHz transducer as an investigative device for the measurement/detection of blood flow in rabbit model. The chapter will describe the procedures for the preparation of sonographer, imaging locations, and the details of the rabbits used as well as detailed imaging steps for the preoperative, immediately after operation, and postoperative follow-up ultrasound for vascular surgery, using a vascular graft implantation as an example. We also provide useful notes to avoid pitfalls for successful imaging. The overall goal of this chapter is to deliver the steps in using low-cost, non-invasive, and highly versatile clinical ultrasound imaging in preclinical small animal testing.

Indexed as

UltrasonographyAnimalsRabbitsConventional ultrasound in animal modelPerioperative ultrasoundPreclinical ultrasoundRabbit vascular graft modelSmall-animal ultrasound

Identifiers

PMID34591309
OpenAlexW3204515758

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.