Evidence map›Paper›PMID 34590794›Full record

ArticlePediatric pulmonology2022

Secondary household transmission of SARS-CoV-2 among children and adolescents: Clinical and epidemiological aspects.

Eliane T Afonso, Solomar M Marques, Lusmaia D C Costa, Patrícia M Fortes, Fernanda Peixoto, Danielli C Bichuetti-Silva, Natália D A Aredes, Claci F W Rosso, Faétila Dos S Oliveira, Fabíola S Fiaccadori and 8 more

Open access · bronzeAbstract read
In one paragraph

Article in Pediatric pulmonology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. The role of children in transmission of SARS-CoV-2 variants of concern within households: an updated systematic review and meta-analysis, as at 30 June 2022.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2023
    Pooled it
  2. The role of children in household transmission of COVID-19: a systematic review and meta-analysis.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022
    Pooled it
  3. Pooled it
  4. Article
  5. Limited transmission of SARS-CoV-2 in schools in Ireland during the 2020-2021 school year.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2023
    Article
  6. Article
  7. Article
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  9. Household transmission of COVID-19 according to index case: children, parents, and healthcare workers.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022
    Article
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  12. [Symptoms of SARS-CoV-2 infections in children of day care age].Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde · 2022
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 1 institution in 1 country.

Eliane T AfonsoDepartment of Pediatrics, Faculty of Medicine, Federal University of Goiás, Goiânia, Goiás, Brazil.
Solomar M MarquesDepartment of Pediatrics, Faculty of Medicine, Federal University of Goiás, Goiânia, Goiás, Brazil.
Lusmaia D C CostaDepartment of Pediatrics, Faculty of Medicine, Federal University of Goiás, Goiânia, Goiás, Brazil.
Patrícia M FortesDepartment of Pediatrics, Faculty of Medicine, Federal University of Goiás, Goiânia, Goiás, Brazil.
Fernanda PeixotoDepartment of Pediatrics, Faculty of Medicine, Federal University of Goiás, Goiânia, Goiás, Brazil.
Danielli C Bichuetti-SilvaDepartment of Pediatrics, Faculty of Medicine, Federal University of Goiás, Goiânia, Goiás, Brazil.
Natália D A AredesFaculty of Nursing, Federal University of Goiás, Goiânia, Goiás, Brazil.
Claci F W RossoFaculty of Nursing, Federal University of Goiás, Goiânia, Goiás, Brazil.
Faétila Dos S OliveiraFaculty of Nursing, Federal University of Goiás, Goiânia, Goiás, Brazil.
Fabíola S FiaccadoriVirology and Cell Culture Laboratory, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia, Goiás, Brazil.
Menira B de L D E SouzaVirology and Cell Culture Laboratory, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia, Goiás, Brazil.
Elisângela de P Silveira-LacerdaDepartment of Genetics, Institute of Biological Sciences, Federal University of Goiás, Goiânia, Goiás, Brazil.
Gabriela S BazilioLaboratory of Clinical Analysis of Higher Education, Institute of Biological Sciences, Federal University of Goiás, Goiânia, Brazil.
Clayton L BorgesDepartment of Biochemistry and Molecular Biology, Institute of Biological Sciences, Federal University of Goiás, Goiânia, Goiás, Brazil.ORCID 0000-0002-9914-8771
Juliana A P RochaDepartment of Biochemistry and Molecular Biology, Institute of Biological Sciences, Federal University of Goiás, Goiânia, Goiás, Brazil.
Alessandra V NaghettiniDepartment of Pediatrics, Faculty of Medicine, Federal University of Goiás, Goiânia, Goiás, Brazil.
Paulo S S da CostaDepartment of Pediatrics, Faculty of Medicine, Federal University of Goiás, Goiânia, Goiás, Brazil.
Rafael A GuimarãesFaculty of Nursing, Federal University of Goiás, Goiânia, Goiás, Brazil.ORCID 0000-0001-5171-7958
Universidade Federal de Goiás · BR

Funding

Ministério da Educação do Brasil
6 · The paper itself

Abstract

objectiveTo evaluate the secondary attack rate (SAR) in children and adolescents, contacts of essential activities workers who were infected by SARS-CoV-2; and to describe associated clinical and epidemiological data.

methodsA cross-sectional study conducted in children and adolescents aged 5 to 19 years of age, that were household contacts of parents and other relatives who were infected by SARS-CoV-2 in the city of Goiânia, Central Brazil, from March to October 2020. Sociodemographic and clinical data were collected from all participants. Nasopharyngeal and oropharyngeal swabs were collected and tested for SARS-CoV-2 RNA using real-time reverse transcription polymerase chain reaction (RT-PCR). Factors associated with SARS-CoV-2 infection and SAR were analyzed using Poisson regression.

resultsA total of 267 children and adolescents were investigated. The prevalence of SARS-CoV-2 RNA by the real-time RT-PCR test and/or the presence of COVID-19 associated symptoms (anosmia/ageusia and flu syndrome) was 25.1% (95.0% Confidence Interval [95.0% CI] = 20.3-30.6). More than half (55.1%) of the participants had sygns and symptoms. The most prevalent signs and symptoms in positive individuals were nasal congestion (62.7%), headache (55.2%), cough (50.8%), myalgia (47.8%), runny nose (47.8%), and anosmia (47.8%). The Poisson model showed that the following signs or symptoms were associated with SARS-CoV-2 infection: fever, nasal congestion, decreased appetite, nausea, anosmia, and ageusia. Families that had more than one infected adult, in addition to the index case, presented greater transmissibility to children and adolescents.

conclusionsOur results contribute to the hypothesis that children and adolescents are not important sources of transmission of SARS-CoV-2 in the home environment during a period of social distancing and school closure; even though they are susceptible to infection in the household (around ¼ of our study population).

Indexed as

COVID-19SARS-CoV-2AdolescentAdultChildCross-Sectional StudiesHome EnvironmentHumansRNA, ViralRNA, ViraladolescentschildrenCOVID-19epidemiologyhousehold infectionsSARS-CoV-2

Identifiers

PMID34590794
PMCPMC8661607
OpenAlexW3203672287

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.