Evidence map›Paper›PMID 34590726›Full record

ArticleMagnetic resonance in medicine2022

Demonstration of fast multi-slice quasi-steady-state chemical exchange saturation transfer (QUASS CEST) human brain imaging at 3T.

Hahnsung Kim, Lisa C Krishnamurthy, Phillip Zhe Sun

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Mitigation of TRadiology advances · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hahnsung KimYerkes Imaging Center, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA.ORCID 0000-0002-0799-6985
Lisa C KrishnamurthyCenter for Visual and Neurocognitive Rehabilitation, Atlanta VA, Decatur, Georgia, USA.
Phillip Zhe SunYerkes Imaging Center, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, USA.ORCID 0000-0003-4872-1192

Funding

Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0M
Establishment of fast pH MRI for imaging metabolic injury during acute strokeR01NS083654 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI Phillip Zhe Sun · 2013 to 2026
$4.0M
Development of glycogen MRI for monitoring of Pompe disease progressionR21AR071529 · NIAMS · EMORY UNIVERSITY · PI SUN, PHILLIP ZHE · 2018 to 2019
$432k
Effects of Acute Exercise on Functional Magnetic Resonance Spectroscopy Measures of GABA in Aging and Chronic StrokeI21RX003581 · VA · VETERANS HEALTH ADMINISTRATION · PI KRISHNAMURTHY, LISA C. · 2021 to 2022
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Beyond lesion-language mapping in aphasia: A novel imaging-based prediction modelIK1RX002629 · VA · VETERANS HEALTH ADMINISTRATION · PI KRISHNAMURTHY, LISA C. · 2019 to 2021
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NIAMS NIH HHS R21 AR071529NIH HHS P51 OD011132NINDS NIH HHS R01 NS083654RRD VA I21 RX003581RRD VA IK1 RX002629
6 · The paper itself

Abstract

purposeTo combine multi-slice chemical exchange saturation transfer (CEST) imaging with quasi-steady-state (QUASS) processing and demonstrate the feasibility of fast QUASS CEST MRI at 3T.

methodsFast multi-slice echo planar imaging (EPI) CEST imaging was developed with concatenated slice acquisition after single radiofrequency irradiation. The multi-slice CEST signal evolution was described by the spin-lock relaxation during saturation duration (T

resultsThe numerical simulation showed that the apparent CEST effect strongly depends on T

conclusionsThe QUASS processing enables fast multi-slice CEST imaging with minimal loss in the measurement of the CEST effect.

Indexed as

Echo-Planar ImagingMagnetic Resonance ImagingAlgorithmsBrainHumansNeuroimagingPhantoms, Imagingchemical exchange saturation transfer (CEST)multi-slicequasi-steady-state (QUASS) CEST

Identifiers

PMID34590726
PMCPMC10214900

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.