Evidence map›Paper›PMID 34590626›Full record

ArticleChemical communications (Cambridge, England)2021

Loquacious-PD regulates the terminus-dependent molecular recognition of Dicer-2 toward double-stranded RNA.

McKenzie Jonely, Raushan K Singh, Helen M Donelick, Brenda L Bass, Rodrigo Noriega

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical communications (Cambridge, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

McKenzie JonelyUniversity of Utah, Department of Chemistry, Salt Lake City, UT 84112, USA. noriega@chem.utah.edu.
Raushan K SinghUniversity of Utah, Department of Biochemistry, Salt Lake City, UT 84112, USA.
Helen M DonelickUniversity of Utah, Department of Biochemistry, Salt Lake City, UT 84112, USA.
Brenda L BassUniversity of Utah, Department of Biochemistry, Salt Lake City, UT 84112, USA.
Rodrigo NoriegaUniversity of Utah, Department of Chemistry, Salt Lake City, UT 84112, USA. noriega@chem.utah.edu.ORCID http://orcid.org/0000-0003-1199-0866

Funding

Elucidating roles and mechanisms of double-stranded RNA-mediated pathwaysR35GM141262 · NIGMS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Brenda L. Bass · 2021 to 2026
$3.7M
Mechanistic insights into Dicer, a double-stranded RNA processing enzymeR01GM121706 · NIGMS · UNIVERSITY OF UTAH · PI BASS, BRENDA L. · 2017 to 2020
$1.5M
NIGMS NIH HHS R01 GM121706NIGMS NIH HHS R35 GM141262
6 · The paper itself

Abstract

Dicer-2 cleaves double-stranded RNA into siRNAs in a terminus-dependent manner as part of

Indexed as

AnimalsCarbocyaninesDrosophila melanogasterDrosophila ProteinsFluorescent DyesRibonuclease IIIRNA-Binding ProteinsRNA, Double-StrandedRNA HelicasesCarbocyaninescyanine dye 3DCR-2 protein, DrosophilaDrosophila ProteinsFluorescent DyesLoqs protein, DrosophilaRibonuclease IIIRNA-Binding ProteinsRNA, Double-StrandedRNA Helicases

Identifiers

PMID34590626
PMCPMC8830880

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.