Evidence map›Paper›PMID 34590614›Full record

ArticleCurrent oncology (Toronto, Ont.)2021

Detection of Cervical Cancer Cells in Whole Slide Images Using Deformable and Global Context Aware Faster RCNN-FPN.

Xia Li, Zhenhao Xu, Xi Shen, Yongxia Zhou, Binggang Xiao, Tie-Qiang Li

Open access · goldAbstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 72 citations in OpenAlex.

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  12. YOLOv7-RAR for Urban Vehicle Detection.Sensors (Basel, Switzerland) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Xia LiInstitute of Information Engineering, China Jiliang University, Hangzhou 310018, China.
Zhenhao XuInstitute of Information Engineering, China Jiliang University, Hangzhou 310018, China.
Xi ShenInstitute of Information Engineering, China Jiliang University, Hangzhou 310018, China.
Yongxia ZhouInstitute of Information Engineering, China Jiliang University, Hangzhou 310018, China.
Binggang XiaoInstitute of Information Engineering, China Jiliang University, Hangzhou 310018, China.
Tie-Qiang LiInstitute of Information Engineering, China Jiliang University, Hangzhou 310018, China.ORCID 0000-0002-4866-5904
Institute of Information Engineering · CNKarolinska University Hospital · SE

Funding

China Scholarship Council, Zhejiang Natural Science Foundation LY18E070005Key Research and Development Program of Zhejiang Province 2020C03020
6 · The paper itself

Abstract

Cervical cancer is a worldwide public health problem with a high rate of illness and mortality among women. In this study, we proposed a novel framework based on Faster RCNN-FPN architecture for the detection of abnormal cervical cells in cytology images from a cancer screening test. We extended the Faster RCNN-FPN model by infusing deformable convolution layers into the feature pyramid network (FPN) to improve scalability. Furthermore, we introduced a global contextual aware module alongside the Region Proposal Network (RPN) to enhance the spatial correlation between the background and the foreground. Extensive experimentations with the proposed deformable and global context aware (DGCA) RCNN were carried out using the cervical image dataset of "Digital Human Body" Vision Challenge from the Alibaba Cloud TianChi Company. Performance evaluation based on the mean average precision (mAP) and receiver operating characteristic (ROC) curve has demonstrated considerable advantages of the proposed framework. Particularly, when combined with tagging of the negative image samples using traditional computer-vision techniques, 6-9% increase in mAP has been achieved. The proposed DGCA-RCNN model has potential to become a clinically useful AI tool for automated detection of cervical cancer cells in whole slide images of Pap smear.

Indexed as

Uterine Cervical NeoplasmsEarly Detection of CancerFemaleHumansNeural Networks, Computercervical cancerfeature pyramid network (FPN)global context aware (GCA)Pap smear testregion based convolutional neural networks (R-CNN)region proposal network (RPN)whole slide image (WSI)

Identifiers

PMID34590614
PMCPMC8482136
OpenAlexW3200847902

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.