Evidence map›Paper›PMID 34590592›Full record

ReviewCurrent oncology (Toronto, Ont.)2021

Ampullary Carcinoma: An Overview of a Rare Entity and Discussion of Current and Future Therapeutic Challenges.

Alessandro Rizzo, Vincenzo Dadduzio, Lucia Lombardi, Angela Dalia Ricci, Gennaro Gadaleta-Caldarola

Registry-linked trialAbstract readReview
In one paragraph

Review in Current oncology (Toronto, Ont.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06648746 (Predictors of Therapeutic Success and Adverse Events in Endoscopic Ampullectomy), which is not on this map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06648746 not yet recruitingnot on this mapstarted 2024, after this paper: background citation

Predictors of Therapeutic Success and Adverse Events in Endoscopic Ampullectomy

TypeobservationalSponsorUniversidade do PortoRan2024 to 2024Enrolled100ConditionsAmpulla of Vater Adenoma, Ampulla of Vater Disease (Benign/Malignancy)
3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. Article
  2. Extrahepatic biliary obstruction due to ampullary carcinoma in a dog.The Journal of veterinary medical science · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Rare, Yet Targetable: New Perspectives on Ampullary Carcinomas.International journal of molecular sciences · 2026
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alessandro RizzoMedical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Albertoni-15, 40128 Bologna, Italy.
Vincenzo DadduzioMedical Oncology Unit, "Mons. R. Dimiccoli" Hospital, 76121 Barletta (BT), ASL BT, Italy.
Lucia LombardiMedical Oncology Unit, "Mons. R. Dimiccoli" Hospital, 76121 Barletta (BT), ASL BT, Italy.
Angela Dalia RicciMedical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Albertoni-15, 40128 Bologna, Italy.
Gennaro Gadaleta-CaldarolaMedical Oncology Unit, "Mons. R. Dimiccoli" Hospital, 76121 Barletta (BT), ASL BT, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ampullary carcinomas (ACs) represent a rare entity, accounting for approximately 0.2% of all gastrointestinal solid tumors and 20% of all periampullary cancers (PACs). Unfortunately, few data are available regarding the optimal therapeutic strategy for ACs due to their rarity, and physicians frequently encounter significant difficulties in the management of these malignancies. In this review, we will provide an overview of current evidence on AC, especially focusing on biological features, histological characteristics, and available data guiding present and future therapeutic strategies for these rare, and still barely known, tumors.

Indexed as

AdenocarcinomaAmpulla of VaterCommon Bile Duct NeoplasmsHumansadenocarcinomaampulla of Vater cancerampullary cancerbiliary tract cancerchemotherapy

Identifiers

PMID34590592
PMCPMC8482111

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.