Evidence map›Paper›PMID 34590520›Full record

ArticleTechnology in cancer research & treatment

Identification of a Signature Comprising 5 Soluble Carrier Family Genes to Predict the Recurrence of Papillary Thyroid Carcinoma.

Rui Han, Wei Sun, Hao Zhang

Open access · goldAbstract read
In one paragraph

Article in Technology in cancer research & treatment. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Rui HanDepartment of Thyroid Surgery, The First Hospital of China Medical University, Shenyang, People's Republic of China.
Wei SunDepartment of Thyroid Surgery, The First Hospital of China Medical University, Shenyang, People's Republic of China.
Hao ZhangDepartment of Thyroid Surgery, The First Hospital of China Medical University, Shenyang, People's Republic of China.
China Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RNA-sequencing data and relevant clinical data in The Cancer Genome Atlas for 502 samples of papillary thyroid cancer (PTC) were analyzed to determine the prognostic value of soluble carrier family genes in PTC. We analyzed soluble carrier family gene expression and function in the samples. Clustering identified 2 clusters in the data. Risk characteristics were identified using LASSO and Univariate Cox regression analysis, which divided the patients into low and high-risk groups. The expression levels of 88 soluble carrier genes were significantly different between tumors and normal tissue. The 2 PTC clusters had different clinical outcomes and distributions of gene expression. The expression levels of

Indexed as

Neoplasm Recurrence, LocalThyroid Cancer, PapillaryThyroid NeoplasmsDatabases, GeneticDisease-Free SurvivalFemaleGene ExpressionHumansK Cl- CotransportersMaleMiddle AgedNeoplasm StagingNucleotide Transport ProteinsOrganic Anion TransportersRisk FactorsSodium-Glucose Transporter 1K Cl- CotransportersNucleotide Transport ProteinsOrganic Anion TransportersSLC35A1 protein, humanSLC35E1 protein, humanSLC5A1 protein, humanSLCO1C1 protein, humanSodium-Glucose Transporter 1Symporterspapillary thyroid carcinomasoluble carrier family genes

Identifiers

PMID34590520
PMCPMC8489750
OpenAlexW3203546589

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.