Evidence map›Paper›PMID 34590519›Full record

ArticleTherapeutic advances in respiratory disease

A new protocol for exercise testing in COPD; improved prediction algorithm for

Ellen Tufvesson, Finn Radner, Anton Simonsen, Georgia Papapostolou, Linnea Jarenbäck, Saga Jönsson, Ulf Nihlen, Alf Tunsäter, Jaro Ankerst, Stefan Peterson and 2 more

Abstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Therapeutic advances in respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ellen TufvessonRespiratory Medicine and Allergology, Department of Clinical Sciences, Lund, Lund University, Skane University Hospital, 221 85 Lund, Sweden.ORCID 0000-0002-4941-332X
Finn RadnerRespiratory Medicine and Allergology, Department of Clinical Sciences, Lund, Lund University, Skane University Hospital, Lund, Sweden.
Anton SimonsenRespiratory Medicine and Allergology, Department of Clinical Sciences, Lund, Lund University, Skane University Hospital, Lund, Sweden.
Georgia PapapostolouRespiratory Medicine and Allergology, Department of Clinical Sciences, Lund, Lund University, Skane University Hospital, Lund, Sweden.
Linnea JarenbäckRespiratory Medicine and Allergology, Department of Clinical Sciences, Lund, Lund University, Skane University Hospital, Lund, Sweden.
Saga JönssonRespiratory Medicine and Allergology, Department of Clinical Sciences, Lund, Lund University, Skane University Hospital, Lund, Sweden.
Ulf NihlenRespiratory Medicine and Allergology, Department of Clinical Sciences, Lund, Lund University, Skane University Hospital, Lund, Sweden.
Alf TunsäterRespiratory Medicine and Allergology, Department of Clinical Sciences, Lund, Lund University, Skane University Hospital, Lund, Sweden.
Jaro AnkerstRespiratory Medicine and Allergology, Department of Clinical Sciences, Lund, Lund University, Skane University Hospital, Lund, Sweden.
Stefan PetersonRegional Cancer Centre South, Region Skane, Lund, Sweden.
Leif BjermerRespiratory Medicine and Allergology, Department of Clinical Sciences, Lund, Lund University, Skane University Hospital, Lund, Sweden.
Göran ErikssonRespiratory Medicine and Allergology, Department of Clinical Sciences, Lund, Lund University, Skane University Hospital, Lund, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTwo new protocols have been developed for bicycle exercise testing in chronic obstructive pulmonary disease (COPD) with an individualized cardiopulmonary exercise test (ICPET) and subsequent customized endurance test (CET), which generate less interindividual spread in endurance time compared with the standard endurance test. Main objectives of this study were to improve the prediction algorithm for

methodsCOPD patients, with forced expiratory volume in 1 s (

resultsThe improved multiple regression algorithm for

conclusionThe two new protocols for ICPET (including the new improved algorithm) and CET were retested with consistent results. In addition, the CET showed a significant and clinically relevant prolongation of endurance time for IND/GLY

Indexed as

Bronchodilator AgentsPulmonary Disease, Chronic ObstructiveAdrenergic beta-2 Receptor AgonistsAlgorithmsDrug CombinationsExercise TestForced Expiratory VolumeGlycopyrrolateHumansIndansLungMuscarinic AntagonistsRandomized Controlled Trials as TopicAdrenergic beta-2 Receptor AgonistsBronchodilator AgentsDrug CombinationsGlycopyrrolateIndansMuscarinic AntagonistsCOPDendurance timeexercise testinglung functionpredictionWMAX

Identifiers

PMID34590519
PMCPMC8488527

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.