Evidence map›Paper›PMID 34590216›Full record

ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2022

Expanded Indication for Magnetic Sphincter Augmentation: Outcomes in Weakly Acidic Reflux Compared to Standard GERD Patients.

Milena Nikolic, Aleksa Matic, Joy Feka, Lisa Gensthaler, Ivan Kristo, Bogdan Osmokrovic, Franz M Riegler, Berta O Mosleh, Sebastian F Schoppmann

Open access · hybridAbstract read
In one paragraph

Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Reflux Testing: Wireless pH, Impedance-pH, and Mucosal Impedance.Gastrointestinal endoscopy clinics of North America · 2025
    Review
  3. Article
  4. Review
  5. The role of magnetic sphincter augmentation in the gastroesophageal reflux disease treatment pathway: the gastroenterology perspective.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2023
    Article
  6. Letter to the Editor: Relevance of a Correct GERD Patient Classification Before Anti-reflux Procedures.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Milena NikolicDepartment of Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Aleksa MaticDepartment of Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Joy FekaDepartment of Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Lisa GensthalerDepartment of Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Ivan KristoDepartment of Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Bogdan OsmokrovicDepartment of Trauma Surgery, Krankenhaus Oberwart, Dornburggasse 80, 7400, Oberwart, Austria.
Franz M RieglerReflux Ordination, Mariannengasse 10/4/9, 1090, Vienna, Austria.
Berta O MoslehDepartment of Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Sebastian F SchoppmannDepartment of Surgery, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria. sebastian.schoppmann@meduniwien.ac.at.
Medical University of Vienna · ATKrankenhaus Oberndorf · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMagnetic sphincter augmentation (MSA) is a modern surgical anti-reflux technique with proven efficacy and low postoperative morbidity in patients with acidic reflux. The aim of this retrospective review study was to evaluate the symptomatic outcome of MSA in patients with weakly acidic reflux.

methodsFrom a prospectively collected clinical database, comprising all 327 patients that underwent MSA at our institution, a total of 67 patients with preoperative weakly acidic reflux measured in the 24-h impedance-pH-metry were identified. Postoperative gastrointestinal symptoms, proton pump inhibitor intake (PPI), GERD Health-Related Quality-of-Life (GERD-HRQL), alimentary satisfaction (AS), and patients' overall satisfaction were evaluated within highly standardized follow-up appointments. Furthermore, outcome of these patients was compared to the postoperative outcome of a comparable group of patients with a preoperative acidic reflux.

resultsAt a median follow-up of 24 months, none of the patients with weakly acidic reflux presented with persistent dysphagia, or underwent endoscopic dilatation or reoperation. The postoperative GERD-HRQL score was significantly reduced (2 vs. 20; p = 0.001) and the median AS was 9/10. Preoperative daily heartburn, regurgitations, and respiratory complaints were improved in 95%, 95%, and 96% of patients, respectively. A total of 10% of the patients continued to use PPIs postoperatively. No significant difference was observed in terms of postoperative outcome or quality of life when comparing weakly acidic reflux patients with those diagnosed with preoperative acidic reflux.

conclusionMagnetic sphincter augmentation significantly improves GERD-related symptoms and quality of life in patients with weakly acidic reflux with very low postoperative morbidity.

Indexed as

Gastroesophageal RefluxLaparoscopyEsophageal Sphincter, LowerFundoplicationHeartburnHumansMagnetic PhenomenaProton Pump InhibitorsQuality of LifeRetrospective StudiesTreatment OutcomeProton Pump InhibitorsGERDHiatal herniaMagnetic sphincter augmentationWeakly acid

Identifiers

PMID34590216
PMCPMC8926968
OpenAlexW3204072290

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.