Evidence map›Paper›PMID 34590043›Full record

ArticleJTO clinical and research reports2021

Evaluating the Content Validity, Clarity, and Relevance of Two Patient-Reported Outcomes for Use With Adults With

Marcia K Horn, Kevin Liu, Susan D Mathias, Hilary H Colwell, Tracy Li, Parthiv Mahadevia, Renee F Pierson

Open access · goldAbstract read
In one paragraph

Article in JTO clinical and research reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. The patient-reported outcomes measurement information systems (PROMIS®) physical function and its derivative measures in adults: a systematic review of content validity.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Marcia K HornInternational Cancer Advocacy Network (ICAN), Phoenix, Arizona.
Kevin LiuJanssen Research & Development LLC, Horsham, Pennsylvania.
Susan D MathiasHealth Outcomes Solutions, Winter Park, Florida.
Hilary H ColwellHealth Outcomes Solutions, Winter Park, Florida.
Tracy LiJanssen Research & Development LLC, Horsham, Pennsylvania.
Parthiv MahadeviaJanssen Research & Development LLC, Horsham, Pennsylvania.
Renee F PiersonJanssen Research & Development LLC, Horsham, Pennsylvania.
Janssen (United States) · USHealth Outcomes Solutions (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNSCLCs account for most lung cancers; approximately 30% involve a mutation in the

methodsPatients with NSCLC from the United States, Europe, and Asia and including those with an exon 20 insertion mutation and other

resultsA total of 30 individuals participated (mean age = 57 years, 87% female, 80% white). The most often reported symptoms included fatigue, shortness of breath, cough, and weight loss. Individuals with the exon 20 insertion mutation (n = 21) more frequently reported negative impacts on daily life, physical functioning, and social functioning but less frequently reported negative impacts to emotional functioning. The PROMIS Short-Form version 2.0-Physical Function 8c and the NSCLC Symptom Assessment Questionnaire were deemed clear, relevant, and easy to complete. The concepts identified during the concept elicitation portion of the interviews were mapped to the content of each PRO, and all items within both PROs were endorsed by at least 20% of the participants.

conclusionsThese results support the content validity, clarity, and relevance of the PROMIS Short-Form version 2.0-Physical Function 8c and the NSCLC Symptom Assessment Questionnaire in a population with

Indexed as

Epidermal growth factor receptorExon 20 insertion mutationNon-small cell lung cancerPatient-reported outcomes

Identifiers

PMID34590043
PMCPMC8474204
OpenAlexW3170740911

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.