Evidence map›Paper›PMID 34589979›Full record

ArticleJTO clinical and research reports2021

Correlating ROS1 Protein Expression With

Richard S P Huang, Amanda Gottberg-Williams, Panhia Vang, Shoua Yang, Nicholas Britt, Jaspreet Kaur, James Haberberger, Natalie Danziger, Clarence Owens, Sara E Beckloff and 2 more

Open access · goldAbstract read
In one paragraph

Article in JTO clinical and research reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Progress of non-small-cell lung cancer withFrontiers in molecular biosciences · 2023
    Review
  5. Article
  6. Current oncology (Toronto, Ont.) · 2022
    Review
  7. Pan-cancer analysis ofJournal for immunotherapy of cancer · 2021
    Article
  8. Pan-cancer landscape ofJournal for immunotherapy of cancer · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Richard S P HuangFoundation Medicine, Inc., Morrisville, North Carolina.
Amanda Gottberg-WilliamsFoundation Medicine, Inc., Morrisville, North Carolina.
Panhia VangFoundation Medicine, Inc., Morrisville, North Carolina.
Shoua YangFoundation Medicine, Inc., Morrisville, North Carolina.
Nicholas BrittFoundation Medicine, Inc., Morrisville, North Carolina.
Jaspreet KaurFoundation Medicine, Inc., Cambridge, Massachusetts.
James HaberbergerFoundation Medicine, Inc., Morrisville, North Carolina.
Natalie DanzigerFoundation Medicine, Inc., Cambridge, Massachusetts.
Clarence OwensFoundation Medicine, Inc., Morrisville, North Carolina.
Sara E BeckloffFoundation Medicine, Inc., Morrisville, North Carolina.
Jeffrey S RossFoundation Medicine, Inc., Cambridge, Massachusetts.
Shakti H RamkissoonFoundation Medicine, Inc., Morrisville, North Carolina.
Foundation Medicine (United States)SUNY Upstate Medical University · USWake Forest University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn this study, we sought to further characterize ROS1 protein expression in solid tumors with the complete spectrum of

methodsROS1 immunohistochemistry (IHC) was performed using the ROS1 (SP384) class I assay per manufacturer's instructions on a variety of solid tumors (n = 32) with known

resultsOf the 32 cases with ROS1 IHC results, 100% (11 of 11) with canonical

conclusionsThese findings suggest that if ROS1 IHC was used as a screening tool for

Indexed as

AmplificationsFusionsMutationsProtein expressionROS1

Identifiers

PMID34589979
PMCPMC8474213
OpenAlexW3087646900

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.