Evidence map›Paper›PMID 34589897›Full record

ArticleBrain, behavior, & immunity - health2020

Gut bacterial taxonomic abundances vary with cognition, personality, and mood in the Wisconsin Longitudinal Study.

Audrey Renson, Lora J Kasselman, Jennifer B Dowd, Levi Waldron, Heidi E Jones, Pamela Herd

Abstract read
In one paragraph

Article in Brain, behavior, & immunity - health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Audrey RensonDepartment of Epidemiology and Biostatistics, CUNY School of Public Health, New York, NY, USA.
Lora J KasselmanDepartment of Epidemiology and Biostatistics, CUNY School of Public Health, New York, NY, USA.
Jennifer B DowdLeverhulme Centre for Demographic Science, University of Oxford, Oxford, UK.
Levi WaldronDepartment of Epidemiology and Biostatistics, CUNY School of Public Health, New York, NY, USA.
Heidi E JonesDepartment of Epidemiology and Biostatistics, CUNY School of Public Health, New York, NY, USA.
Pamela HerdMcCourt School of Public Policy, Georgetown University, Washington, DC, 20057, USA.

Funding

Wisconsin longitudinal study: Initial lifetime's impact on Alzheimer's disease and related disorders (WLS-ILIAD)R01AG060737 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI Sanjay Asthana, Michal Engelman · 2018 to 2026
$56.8M
NIA NIH HHS R01 AG060737
6 · The paper itself

Abstract

Animal studies have shown that the gut microbiome can influence memory, social behavior, and anxiety-like behavior. Several human studies show similar results where variation in the gut microbiome is associated with dementia, depression, and personality traits, though most of these studies are limited by small sample size and other biases. Here, we analyzed fecal samples from 313 participants in the Wisconsin Longitudinal Study, a randomly selected population-based cohort of older adults, with measured psycho-cognitive dimensions (cognition, mood, and personality) and key confounders. 16s V4 sequencing showed that

Indexed as

CohortDepressionFive-factorGut bacteriaGut-brainMemory

Identifiers

PMID34589897
PMCPMC8474555

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.