ReviewBrain, behavior, & immunity - health2020
Stressful experiences in youth: "Set-up" for diminished resilience to chronic pain.
Review in Brain, behavior, & immunity - health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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Who cites it
13 citing papers in PubMed, 23 citations in OpenAlex.
- Investigating associations between allostatic load phenotypes and clinical impairment in youth with chronic pain.Brain, behavior, & immunity - health · 2026Article
- The greater the pleiotropic effects, the greater the benefits - cannabis as a "biopsychosocial" drug: a mixed-methods study on chronic non-cancer pain.Journal of cannabis research · 2026Article
- Neuroinflammation and Pediatric Chronic Pain - A Review.Current pain and headache reports · 2026Review
- Resting-state cortical activity, biomarkers and functional performance identify distinct biopsychosocial phenotypes in young adults with chronic postsurgical pain.Frontiers in pain research (Lausanne, Switzerland) · 2026Article
- Expanding the Lens: Recent Developments at the Intersection of Pediatric Chronic Pain and Gender Diversity.Current pain and headache reports · 2025Review
- Medical Post-Traumatic Stress Disorder Symptoms in Children and Adolescents with Chronic Inflammatory Arthritis: Prevalence and Associated Factors.Children (Basel, Switzerland) · 2025Article
- Overview: Chronic Pain and Cannabis-Based Medicines.Pharmacopsychiatry · 2024Review
- Chronic Pain in Autistic Youth: Clinical Prevalence and Reflections on Tailoring Evidence-Based Interventions from an Interdisciplinary Treatment Team.Children (Basel, Switzerland) · 2024Article
- Traumatic Events, Posttraumatic Stress Disorder, and Central Sensitization in Chronic Pain Patients of a German University Outpatient Pain Clinic.Psychosomatic medicine · 2023Article
- Paediatric chronic pain as a catalyst for toxic stress.The Lancet. Child & adolescent health · 2022Article
- A Scoping Review and Proposed Framework for Coping in Youth With a History of Psychological Trauma and Chronic Pain.Journal of pediatric psychology · 2022Article
- Biomarkers of Allostatic Load as Correlates of Impairment in Youth with Chronic Pain: An Initial Investigation.Children (Basel, Switzerland) · 2021Article
- Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic pain in youth is common, with prevalence rates in some reports exceeding 50%. Given the plasticity of brain systems in youth and their general level of activity, the underlying processes relating to the evolution of chronic pain may be different from that observed in adults. One aspect that affects brain development is childhood stress. Preliminary research indicates that maladaptive responses to stressful events that induce biological and psychological inability to adapt may be related to pain chronicity in youth. This relationship is particularly notable given the high rates of exposure to stressful events in pediatric pain populations. A review of the literature was performed in the areas of biological, cognitive, psychological and social processes associated with chronic pain and psychological stress and trauma in youth and adult populations. The current review presents a theoretical framework, adapted from McEwen's model (1998) on stress and allostatic load, which aims to outline the potential connection between exposure to stressful events and pediatric chronic pain. Avenues for future investigation are also identified.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.