ArticleBrain, behavior, & immunity - health2020
Acute intake of
Article in Brain, behavior, & immunity - health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- Efficacy and safety of gut microbiome-targeted treatment in patients with depression: a systematic review and meta-analysis.BMC psychiatry · 2025Pooled it
- Examining the Influence of the Human Gut Microbiota on Cognition and Stress: A Systematic Review of the Literature.Nutrients · 2022Pooled it
- Exploring the impact of probiotics on adult ADHD management through a double-blind RCT.Scientific reports · 2024Trial
- Trial
- Modulating depression through the gut-brain axis: the role of gut microbiota in therapeutic interventions.Naunyn-Schmiedeberg's archives of pharmacology · 2025Review
- The Impact of Gut Microbiota on the Development of Anxiety Symptoms-A Narrative Review.Nutrients · 2025Review
- Probiotics and Prebiotics Affecting Mental and Gut Health.Healthcare (Basel, Switzerland) · 2024Article
- Influence and Selection of Probiotics on Depressive Disorders in Occupational Health: Scoping Review.Nutrients · 2023Article
- Gut Biome and Mental Health: Do Probiotics Work?Cureus · 2023Review
- Relationship between psychosocial stress-induced prefrontal cortex activity and gut microbiota in healthy Participants-A functional near-infrared spectroscopy study.Neurobiology of stress · 2022Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe gut microbiome communicates bidirectionally with the brain, linking the gut to psychological phenomena such as stress, depression, and anxiety. Probiotics, or ingestible supplements containing billions of mutualistic bacteria, have demonstrated the mechanistic potential to influence mood; however, few studies have experimentally examined the acute effects of these compounds on individuals not recruited for psychopathology or gut dysfunction. The present study hypothesized reductions in stress, anxiety and depression symptoms following an acute, one week dosing period of
methodsThe efficacy of a one-week period of orally administered
resultsNo significant reduction in symptoms between groups over the one-week period was found.
conclusionsThese findings suggest that 7-days of B. longum does not reduce stress, depressive symptoms, or anxiety in generally healthy young adults.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.